G Protein-Coupled Receptor 20 (GPR20) is a protein in humans encoded by the GPR20 gene. This protein belongs to the family of G protein-coupled receptors (GPCRs), which are involved in transmitting signals across cell membranes. GPCRs are a large and diverse group of proteins that play crucial roles in many different biological processes and are targets for a large number of drugs.GPCRs function by binding to specific molecules outside the cell (ligands), which causes a conformational change in the receptor and initiates a series of events inside the cell. These intracellular events, often involving the activation of G proteins, lead to a cellular response.
Many GPCRs have unknown ligands and are referred to as orphan receptors until their ligand is discovered. GPR20 falls into this category.In terms of disease associations there is limited information about GPR20. Some studies suggest potential links between variations in the GPR20 gene and certain phenotypic traits or disease susceptibilities, but these associations are not yet well established and require further investigation.In summary, GPR20 is a G protein-coupled receptor with an as-yet unknown specific ligand and function. Its potential involvement in disease and its role within the broader context of GPCR signaling are areas of ongoing research. This makes GPR20 an interesting target for further study, as understanding its function could provide new insights into cellular signaling and potential targets.
产品名称 | CAS # | 产品编号 | 数量 | 价格 | 应用 | 排名 |
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Pilocarpine | 92-13-7 | sc-479256 | 100 mg | $250.00 | 1 | |
毒蕈碱受体激动剂 Pilocarpine 可调节 GPCR 信号,间接影响 GPR20。 | ||||||
Adenosine | 58-61-7 | sc-291838 sc-291838A sc-291838B sc-291838C sc-291838D sc-291838E sc-291838F | 1 g 5 g 100 g 250 g 1 kg 5 kg 10 kg | $33.00 $47.00 $294.00 $561.00 $1020.00 $2550.00 $4590.00 | 1 | |
腺苷能激活腺苷受体(GPCR 家族的一部分),从而可能影响与 GPR20 相关的途径。 | ||||||
Dopamine | 51-61-6 | sc-507336 | 1 g | $290.00 | ||
多巴胺通过对多巴胺受体的作用,可能会间接影响 GPR20 信号的传递。 | ||||||
Oxytocin acetate salt | 50-56-6 | sc-279938 sc-279938A sc-279938B sc-279938C sc-279938D sc-279938E | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $59.00 $176.00 $330.00 $650.00 $950.00 $1800.00 | 4 | |
另一种 GPCR 配体催产素可能会对 GPR20 的功能产生间接影响。 | ||||||
3-(2-Aminoethyl)-1H-indol-5-ol | 50-67-9 | sc-298707 | 1 g | $520.00 | 3 | |
羟色胺通过对羟色胺受体(GPCR)的作用,可能会间接影响 GPR20。 | ||||||
Histamine, free base | 51-45-6 | sc-204000 sc-204000A sc-204000B | 1 g 5 g 25 g | $92.00 $277.00 $969.00 | 7 | |
组胺作用于组胺受体(GPCRs 的一部分),可以间接调节 GPR20 的活性。 |