Trioxsalen A photochemical crosslinker of DNA that has been used as a probe for nucleic acid structure and function. Trioxsalen has also been used to crosslink DNA onto mica surfaces.

Trioxsalen  (CAS 3902-71-4)

Trioxsalen is rated 5.0 out of 5 by 1.
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Synonym: 2,5,9-Trimethylfuro[3,2-g]benzopyran-7-one; 4,5′,8-Trimethylpsoralen; TMP; Trisoralen
Application: A photochemical crosslinker of DNA used as a probe for nucleic acid structure
CAS Number: 3902-71-4
Purity: 99%
Molecular Weight: 228.24
Molecular Formula: C14H12O3
* Refer to Certificate of Analysis for lot specific data (including water content).
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Ordering Information

PRODUCT NAME CATALOG # UNIT PRICE QTY FAVORITES
Trioxsalen sc-216017 1 g $47.00
Trioxsalen sc-216017A 5 g $186.00

Trioxsalen is a photochemical crosslinker of DNA that has been used as a probe for nucleic acid structure and function. Trioxsalen has also been used to crosslink DNA onto mica surfaces.


References

Shlyakhtenko, L.S., et al., Atomic force microscopy imaging of DNA covalently immobilized on a functionalized mica substrate. Biophys. J. 77, 568-576, (1999); G.D. Cimino Annu. Rev. Biochem. 54, 1151, (1985); Botta, R., and Gustavino, B., Relationship between chromatin bridges in anaphase and chromosomal aberrations induced by TMP + UVA (365 nm) in CHO cells. Mutat. Res. 374, 253-259, (1997); Mojica, F.J., and Higgins, C.F., Localized domains of DNA supercoiling: topological coupling between promoters. Mol. Microbiol. 22, 919, (1996);

Appearance :
Powder
Physical State :
Solid
Solubility :
Methylene Chloride
Storage :
Store at -20° C
Melting Point :
229-231° C (lit.)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Transport :
UN 1759, Class 8, Packing group I
PubChem CID :
5585
SMILES :
CC1=CC(=O)OC2=C1C=C3C=C(OC3=C2C)C

Download SDS (MSDS)

Certificate of Analysis

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Rated 5 out of 5 by from Nilsen et al Nilsen et al. (PubMed ID 25183819) found that trioxsalent, a psoralen derivative, was capable of detecting RNA-RNA interactions in tissue culture cells or in extracts by reducing mobility in polyacrylamide gels. -SCBT Publication Review
Date published: 2015-06-26
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