Date published: 2025-10-10

1-800-457-3801

SCBT Portrait Logo
Seach Input

Spermidine (CAS 124-20-9)

4.5(2)
Write a reviewAsk a question

Alternate Names:
N-(3-Aminopropyl)-1,4-diaminobutane
Application:
Spermidine is a NOS1 inhibitor and NMDA and T4 polynucleotide kinase activator
CAS Number:
124-20-9
Purity:
99%
Molecular Weight:
145.25
Molecular Formula:
C7H19N3
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

Spermidine inhibits NOS1 (nNOS). Spermidine binds and precipitates DNA and may be used for purification of DNA binding proteins. Spermidine activates PNK (polynucleotide kinase T4). Spermidine binds to and activates NMDA and may act to potentiate NMDA-induced currents in a concentration-dependent manner.


Spermidine (CAS 124-20-9) References

  1. Spermidine synthase genes are essential for survival of Arabidopsis.  |  Imai, A., et al. 2004. Plant Physiol. 135: 1565-73. PMID: 15247389
  2. Induction of autophagy by spermidine promotes longevity.  |  Eisenberg, T., et al. 2009. Nat Cell Biol. 11: 1305-14. PMID: 19801973
  3. Preparation of extracts from prokaryotes.  |  Cull, M. and McHenry, CS. 1990. Methods Enzymol. 182: 147-53. PMID: 2107372
  4. Spermidine and resveratrol induce autophagy by distinct pathways converging on the acetylproteome.  |  Morselli, E., et al. 2011. J Cell Biol. 192: 615-29. PMID: 21339330
  5. Anti-inflammatory effects of spermidine in lipopolysaccharide-stimulated BV2 microglial cells.  |  Choi, YH. and Park, HY. 2012. J Biomed Sci. 19: 31. PMID: 22433014
  6. A DNA polymerase from embryos of Drosophila melanogaster. Purification and properties.  |  Karkas, JD., et al. 1975. J Biol Chem. 250: 8657-63. PMID: 241752
  7. First-strand cDNA synthesis primed with oligo(dT).  |  Krug, MS. and Berger, SL. 1987. Methods Enzymol. 152: 316-25. PMID: 2443800
  8. Biosynthetic arginine decarboxylase from Escherichia coli. Purification and properties.  |  Wu, WH. and Morris, DR. 1973. J Biol Chem. 248: 1687-95. PMID: 4571773
  9. Argenine decarboxylase from Escherichia coli. I. Purification and specificity for substrates and coenzyme.  |  Blethen, SL., et al. 1968. J Biol Chem. 243: 1671-7. PMID: 4870599
  10. Polyamines.  |  Tabor, CW. and Tabor, H. 1984. Annu Rev Biochem. 53: 749-90. PMID: 6206782
  11. The effect of spermidine on endonuclease inhibition by agarose contaminants.  |  Bouché, JP. 1981. Anal Biochem. 115: 42-5. PMID: 6272602
  12. Polyamines inhibit nitric oxide synthase in rat cerebellum.  |  Hu, J., et al. 1994. Neurosci Lett. 175: 41-5. PMID: 7526294
  13. Purification of human Rad51 protein by selective spermidine precipitation.  |  Baumann, P., et al. 1997. Mutat Res. 384: 65-72. PMID: 9298115

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Spermidine, 1 g

sc-215900
1 g
$56.00

Spermidine, 5 g

sc-215900A
5 g
$173.00

Spermidine, 25 g

sc-215900B
25 g
$595.00

I received this product as a liquid and need to know its Molarity for experimental calculations. However, there is no mention of the total volume of this liquid to use for calculations. What is the Molarity of this when it arrives?

Asked by: Melissa234
Thank you for your question. Please contact your local distributor or technical service for further assistance.
Answered by: Tech Service 1
Date published: 2021-08-19

How long does it take to get spermidine delivered?

Asked by: christine03
Thank you for your question. Please contact our Customer Care Department to inquire about current product availability and shipping lead times to the Philippines. Please call us toll-free at (800) 457-3801 option 1, e-mail <customercare@scbt.com>, or use the live chat on our website.
Answered by: Technical Support
Date published: 2021-08-19
  • y_2025, m_10, d_9, h_7CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_2
  • loc_en_US, sid_215900, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 132ms
  • QUESTIONS, PRODUCT
Rated 4 out of 5 by from Great featuresI am starting a new program and wish to test several new products for a different outcome.
Date published: 2019-06-11
Rated 5 out of 5 by from Wu et alWu et al. (PubMed ID 4571773) showed spermidine inhibited biosynthetic arginine decarboxyalse feedback by blocking putrescine. -SCBT Publication Review
Date published: 2015-07-07
  • y_2025, m_10, d_9, h_7
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_2
  • loc_en_US, sid_215900, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 17ms
  • REVIEWS, PRODUCT
Spermidine is rated 4.5 out of 5 by 2.
  • y_2025, m_10, d_9, h_7
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_2
  • loc_en_US, sid_215900, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 115ms
  • REVIEWS, PRODUCT