Date published: 2025-10-19

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(S)-ar-Turmerone (CAS 532-65-0)

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Alternate Names:
(+)-ar-Turmerone
Application:
(S)-ar-Turmerone is an antitumor and antiinflammatory agent
CAS Number:
532-65-0
Molecular Weight:
216.32
Molecular Formula:
C15H20O
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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(S)-ar-Turmerone is a naturally occurring compound found in turmeric. It belongs to the class of sesquiterpenes and possesses distinct properties and applications in scientific research. (S)-ar-Turmerone is renowned for its antioxidant and anti-inflammatory properties. It is one of the major constituents present in the essential oil from the rhizomes of Curcuma longa, a perennial plant belonging to the ginger family, Zingiberaceae. In scientific applications, (S)-ar-Turmerone has gained attention for its diverse effects on various biological processes. It exhibits antitumor activity, demonstrating a cytotoxic effect specifically on cancer cells. This compound acts as an immune activator, stimulating the proliferation of peripheral blood mononuclear cells and enhancing the production of important immune-related molecules such as TNF-α, IL-2, and IFN-γ. Additionally, (S)-ar-Turmerone promotes the maturation of dendritic cells, players in the immune system response. Furthermore, (S)-ar-Turmerone has shown promising effects on neural stem cells, both in vitro and in vivo, by inducing their proliferation. This suggests potential applications in the field of regenerative medicine and neurobiology. The exact mechanism of action of (S)-ar-Turmerone is not fully elucidated. However, its observed effects are attributed to its interactions with various cellular signaling pathways, including those involved in immune modulation and cell growth regulation.


(S)-ar-Turmerone (CAS 532-65-0) References

  1. Stereospecific Pd(0)-catalyzed arylation of an allylic hydroxy phosphonate derivative: formal synthesis of (S)-(+)-ar-turmerone.  |  Rowe, BJ. and Spilling, CD. 2003. J Org Chem. 68: 9502-5. PMID: 14629182
  2. Acetylcholinesterase inhibitory activity of volatile oil from Peltophorum dasyrachis Kurz ex Bakar (yellow batai) and Bisabolane-type sesquiterpenoids.  |  Fujiwara, M., et al. 2010. J Agric Food Chem. 58: 2824-9. PMID: 20146521
  3. Biotransformation of turmerones by Aspergillus niger.  |  Fujiwara, M., et al. 2011. J Nat Prod. 74: 86-9. PMID: 21189039
  4. Cobalt-bisoxazoline-catalyzed asymmetric Kumada cross-coupling of racemic α-bromo esters with aryl Grignard reagents.  |  Mao, J., et al. 2014. J Am Chem Soc. 136: 17662-8. PMID: 25479180
  5. Highly Efficient Enantioselective Synthesis of Chiral Sulfones by Rh-Catalyzed Asymmetric Hydrogenation.  |  Yan, Q., et al. 2019. J Am Chem Soc. 141: 1749-1756. PMID: 30615423

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(S)-ar-Turmerone, 1 mg

sc-491935A
1 mg
$140.00

(S)-ar-Turmerone, 5 mg

sc-491935B
5 mg
$750.00

(S)-ar-Turmerone, 10 mg

sc-491935
10 mg
$800.00