Date published: 2025-9-15

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Pterine (CAS 2236-60-4)

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Alternate Names:
2-Amino-4-hydroxypteridine, 2-Amino-4-oxodihydropteridine, Pterin
CAS Number:
2236-60-4
Purity:
≥95%
Molecular Weight:
163.14
Molecular Formula:
C6H5N5O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Pterine, a naturally occurring compound found in plants, animals, and bacteria, holds significant importance as a cofactor in various biochemical pathways. It plays a vital role in the synthesis of nucleic acids, proteins, carbohydrate metabolism, and lipid metabolism. Additionally, Pterine contributes to gene expression regulation and signal transduction processes. Regarding its mechanisms of action, Pterine acts as a cofactor in biochemical pathways that govern nucleic acid and protein synthesis, as well as carbohydrate and lipid metabolism. It also actively participates in gene expression regulation and signal transduction. In the context of gene expression, Pterine binds to DNA and functions as a transcription factor, modulating gene expression levels. During signal transduction, Pterine binds to cell surface receptors, triggering activation or inhibition of receptor activity, ultimately influencing cellular functions.


Pterine (CAS 2236-60-4) References

  1. Pterin transport and metabolism in Leishmania and related trypanosomatid parasites.  |  Ouellette, M., et al. 2002. Int J Parasitol. 32: 385-98. PMID: 11849635
  2. Excited flavin and pterin coenzyme molecules in evolution.  |  Kritsky, MS., et al. 2010. Biochemistry (Mosc). 75: 1200-16. PMID: 21166638
  3. Synthesis of biopterin and related pterin glycosides.  |  Hanaya, T. and Yamamoto, H. 2013. IUBMB Life. 65: 300-9. PMID: 23436386
  4. Tryptophan oxidation photosensitized by pterin.  |  Thomas, AH., et al. 2013. Free Radic Biol Med. 63: 467-75. PMID: 23747929
  5. The biosynthesis of the molybdenum cofactors.  |  Mendel, RR. and Leimkühler, S. 2015. J Biol Inorg Chem. 20: 337-47. PMID: 24980677
  6. A Prebiotic Synthesis of Pterins.  |  Marín-Yaseli, MR., et al. 2015. Chemistry. 21: 13531-4. PMID: 26256284
  7. Analeptic agent from microbes upon cyanide degradation.  |  Murugesan, T., et al. 2018. Appl Microbiol Biotechnol. 102: 1557-1565. PMID: 29285551
  8. Analysis of Catecholamines and Pterins in Inborn Errors of Monoamine Neurotransmitter Metabolism-From Past to Future.  |  Jung-Klawitter, S. and Kuseyri Hübschmann, O. 2019. Cells. 8: PMID: 31405045
  9. Chemical Modifications of Globular Proteins Phototriggered by an Endogenous Photosensitizer.  |  Reid, LO., et al. 2019. Chem Res Toxicol. 32: 2250-2259. PMID: 31588735
  10. Pterin-photosensitization of thymine under anaerobic conditions in the presence of guanine.  |  Estébanez, S., et al. 2021. Free Radic Biol Med. 174: 321-328. PMID: 34339797
  11. Pterin-based pigmentation in animals.  |  Andrade, P. and Carneiro, M. 2021. Biol Lett. 17: 20210221. PMID: 34403644
  12. Synthesis, Redox and Spectroscopic Properties of Pterin of Molybdenum Cofactors.  |  Colston, KJ. and Basu, P. 2022. Molecules. 27: PMID: 35630801
  13. Insights into Molecular Structure of Pterins Suitable for Biomedical Applications.  |  Buglak, AA., et al. 2022. Int J Mol Sci. 23: PMID: 36499560
  14. Unveiling Photodegradation and Photosensitization Mechanisms of Unconjugated Pterins.  |  Arpa, EM. and Corral, I. 2023. Chemistry. 29: e202300519. PMID: 36929221
  15. Studies on the degradation of pterine and pterine-6-carboxylic acid by Pseudomonas fluorescens UK-1.  |  Soini, J. and Backman, A. 1975. Acta Chem Scand B. 29: 710-4. PMID: 811029

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Pterine, 100 mg

sc-215759
100 mg
$59.00

Pterine, 250 mg

sc-215759A
250 mg
$95.00