Molecular structure of Imazalil, CAS Number: 35554-44-0
Imazalil (CAS 35554-44-0)
See product citations (2)
Application:
Imazalil is an antifungal agent that may have carcinogenic potential
CAS Number:
35554-44-0
Purity:
≥95%
Molecular Weight:
297.18
Molecular Formula:
C14H14Cl2N2O
Supplemental Information:
This is as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Imazalil exhibits antifungal activity through inhibition of sterol 14-α demethylase, preventing ergosterol biosynthesis and cell wall formation. Imazalil also inhibits androgen receptors and aromatase through a mixed competitive/noncompetitive mode in vitro. Imazalil exhibits teratogenic effects on vertebrate development, affecting genes involved in retinoic acid signaling and altering neural differentiation in the nervous system.
Imazalil (CAS 35554-44-0) References
- Induction and inhibition of aromatase (CYP19) activity by various classes of pesticides in H295R human adrenocortical carcinoma cells. | Sanderson, JT., et al. 2002. Toxicol Appl Pharmacol. 182: 44-54. PMID: 12127262
- Enantioseparation of imazalil residue in orange by capillary electrophoresis with 2-hydroxypropyl-beta-cyclodextrin as a chiral selector. | Kodama, S., et al. 2003. J Agric Food Chem. 51: 6128-31. PMID: 14518933
- Effects of the azole fungicide Imazalil on the development of the ascidian Ciona intestinalis (Chordata, Tunicata): morphological and molecular characterization of the induced phenotype. | Zega, G., et al. 2009. Aquat Toxicol. 91: 255-61. PMID: 19124165
- PdCYP51B, a new putative sterol 14α-demethylase gene of Penicillium digitatum involved in resistance to imazalil and other fungicides inhibiting ergosterol synthesis. | Sun, X., et al. 2011. Appl Microbiol Biotechnol. 91: 1107-19. PMID: 21637936
- Competitive androgen receptor antagonism as a factor determining the predictability of cumulative antiandrogenic effects of widely used pesticides. | Orton, F., et al. 2012. Environ Health Perspect. 120: 1578-84. PMID: 23008280
- Follow-up of the fate of imazalil from post-harvest lemon surface treatment to a baking experiment. | Vass, A., et al. 2015. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 32: 1875-84. PMID: 26365625
- Degradation of imazalil, orthophenylphenol and pyrimethanil in Clementine mandarins under conventional postharvest industrial conditions at 4°C. | Besil, N., et al. 2016. Food Chem. 194: 1132-7. PMID: 26471663
- Acceleration of murine hepatocyte proliferation by imazalil through the activation of nuclear receptor PXR. | Yoshimaru, S., et al. 2018. J Toxicol Sci. 43: 443-450. PMID: 29973476
- Genotoxicity of mixture of imidacloprid, imazalil and tebuconazole. | Ilyushina, NA., et al. 2020. Toxicol Rep. 7: 1090-1094. PMID: 32953461
- Ecotoxicological evaluation of imazalil transformation products on Eisenia Andrei. | Correia, FV., et al. 2021. Ecotoxicology. 30: 198-212. PMID: 33566272
- Monitoring the behavior of imazalil and its metabolite in grapes, apples, and the processing of fruit wine at enantiomeric level. | Li, R., et al. 2021. J Sci Food Agric. 101: 5478-5486. PMID: 33682082
- Imazalil and its metabolite imazalil-M caused developmental toxicity in zebrafish (Danio rerio) embryos via cell apoptosis mediated by metabolic disorders. | Huang, S., et al. 2022. Pestic Biochem Physiol. 184: 105113. PMID: 35715052
- Stereoselective behavior and residues of the imazalil during strawberry growth and strawberry wine production. | Zhang, J., et al. 2023. J Food Prot. 86: 100006. PMID: 36916581
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Imazalil, 5 g | sc-204775 | 5 g | $112.00 | |||
Imazalil, 10 g | sc-204775A | 10 g | $142.00 | |||
Imazalil, 100 g | sc-204775B | 100 g | $848.00 |