Molecular structure of Hypotaurine, CAS Number: 300-84-5
Hypotaurine (CAS 300-84-5)
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Alternate Names:
2-Aminoethylsulfinic acid
Application:
Hypotaurine is an endogenous inhibitory signaling amino acid
CAS Number:
300-84-5
Molecular Weight:
109.14
Molecular Formula:
C2H7NO2S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Hypotaurine is an organic compound known for its antioxidant properties, particularly in research applications. It effectively scavenges free radicals and reactive oxygen species (ROS), crucial agents of oxidative damage to cells and tissues. By donating electrons, hypotaurine neutralizes these harmful radicals, preventing them from causing cellular harm. This action stabilizes ROS and mitigates their ability to induce oxidative stress, crucial for maintaining cellular redox balance. Through these mechanisms, hypotaurine helps preserve cell integrity and function, making it an essential tool in studying the effects of oxidative stress on biological systems.
Hypotaurine (CAS 300-84-5) References
- Taurine and hypotaurine in spermatozoa and epididymal fluid of cats. | Buff, S., et al. 2001. J Reprod Fertil Suppl. 57: 93-5. PMID: 11787195
- Glutamine and hypotaurine improves intracellular oxidative status and in vitro development of porcine preimplantation embryos. | Suzuki, C., et al. 2007. Zygote. 15: 317-24. PMID: 17967211
- The effects of taurine, taurine homologs and hypotaurine on cell and membrane antioxidative system alterations caused by type 2 diabetes in rat erythrocytes. | Gossai, D. and Lau-Cam, CA. 2009. Adv Exp Med Biol. 643: 359-68. PMID: 19239167
- Comparison of the protective actions of N-acetylcysteine, hypotaurine and taurine against acetaminophen-induced hepatotoxicity in the rat. | Acharya, M. and Lau-Cam, CA. 2010. J Biomed Sci. 17 Suppl 1: S35. PMID: 20804611
- Hypotaurine evokes a malignant phenotype in glioma through aberrant hypoxic signaling. | Gao, P., et al. 2016. Oncotarget. 7: 15200-14. PMID: 26934654
- The antioxidant action of taurine, hypotaurine and their metabolic precursors. | Aruoma, OI., et al. 1988. Biochem J. 256: 251-5. PMID: 2851980
- The Effect of L-Carnitine, Hypotaurine, and Taurine Supplementation on the Quality of Cryopreserved Chicken Semen. | Partyka, A., et al. 2017. Biomed Res Int. 2017: 7279341. PMID: 28523277
- Flavin-Containing Monooxygenase 1 Catalyzes the Production of Taurine from Hypotaurine. | Veeravalli, S., et al. 2020. Drug Metab Dispos. 48: 378-385. PMID: 32156684
- Taurine, hypotaurine, epinephrine and albumin inhibit lipid peroxidation in rabbit spermatozoa and protect against loss of motility. | Alvarez, JG. and Storey, BT. 1983. Biol Reprod. 29: 548-55. PMID: 6626644
- Effects of epinephrine and hypotaurine on in-vitro fertilization in the golden hamster. | Leibfried, ML. and Bavister, BD. 1982. J Reprod Fertil. 66: 87-93. PMID: 7120204
- Effect of sucrose, trehalose, hypotaurine, taurine, and blood serum on survival of frozen bull sperm. | Chen, Y., et al. 1993. Cryobiology. 30: 423-31. PMID: 8403993
Activator of:
GlyR, and Rhodanese.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Hypotaurine, 100 mg | sc-204005 | 100 mg | $52.00 |