Heptadecanoic acid (CAS 506-12-7)
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Heptadecanoic acid is a saturated fatty acid that functions as a precursor for the biosynthesis of various lipids and as a substrate for the production of energy in cells. It plays a role in lipid metabolism, serving as a building block for the synthesis of complex lipids such as triglycerides and phospholipids. Within cells, heptadecanoic acid undergoes beta-oxidation, a process in which it is broken down to generate acetyl-CoA, which enters the citric acid cycle to produce ATP, the primary energy currency of the cell. Heptadecanoic acid can modulate gene expression and signal transduction pathways involved in lipid homeostasis and inflammation. At the molecular level, it interacts with various enzymes and transport proteins to regulate lipid synthesis and metabolism.
Heptadecanoic acid (CAS 506-12-7) References
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- A review of odd-chain fatty acid metabolism and the role of pentadecanoic Acid (c15:0) and heptadecanoic Acid (c17:0) in health and disease. | Jenkins, B., et al. 2015. Molecules. 20: 2425-44. PMID: 25647578
- Pentadecanoic and Heptadecanoic Acids: Multifaceted Odd-Chain Fatty Acids. | Pfeuffer, M. and Jaudszus, A. 2016. Adv Nutr. 7: 730-4. PMID: 27422507
- Milk fat biomarkers and cardiometabolic disease. | Risérus, U. and Marklund, M. 2017. Curr Opin Lipidol. 28: 46-51. PMID: 27906713
- Peroxisomal 2-Hydroxyacyl-CoA Lyase Is Involved in Endogenous Biosynthesis of Heptadecanoic Acid. | Jenkins, B., et al. 2017. Molecules. 22: PMID: 29027957
- Heptadecanoic acid as an indicator of BCFA content in sheep fat. | Watkins, PJ. and Frank, D. 2019. Meat Sci. 151: 33-35. PMID: 30684848
- Heptadecanoic acid inhibits cell proliferation in PC‑9 non‑small‑cell lung cancer cells with acquired gefitinib resistance. | Xu, C., et al. 2019. Oncol Rep. 41: 3499-3507. PMID: 31002344
- High-resolution metabolomic biomarkers for lung cancer diagnosis and prognosis. | Qi, SA., et al. 2021. Sci Rep. 11: 11805. PMID: 34083687
- Recovery of Fatty Acid Monolayers by Salts Investigated by Sum-Frequency Generation Spectroscopy. | Sam, S., et al. 2022. J Phys Chem B. 126: 643-649. PMID: 35026947
- Heptadecanoic acid and pentadecanoic acid crosstalk with fecal-derived gut microbiota are potential non-invasive biomarkers for chronic atrophic gastritis. | Gai, X., et al. 2022. Front Cell Infect Microbiol. 12: 1064737. PMID: 36699724
- Heptadecanoic Acid, an Odd-Chain Fatty Acid, Induces Apoptosis and Enhances Gemcitabine Chemosensitivity in Pancreatic Cancer Cells. | Kim, HY., et al. 2023. J Med Food. 26: 201-210. PMID: 36716276
- Heptadecanoic Acid Is Not a Key Mediator in the Prevention of Diet-Induced Hepatic Steatosis and Insulin Resistance in Mice. | Bishop, CA., et al. 2023. Nutrients. 15: PMID: 37432205
- Kinetics of radioiodinated heptadecanoic acid and metabolites in the normal and ischaemic canine heart. | Visser, FC., et al. 1985. Eur Heart J. 6 Suppl B: 97-101. PMID: 4085512
- Beta-methyl[1-11C]heptadecanoic acid: a new myocardial metabolic tracer for positron emission tomography. | Livni, E., et al. 1982. J Nucl Med. 23: 169-75. PMID: 6977020
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Heptadecanoic acid, 1 g | sc-215139 | 1 g | $40.00 | |||
Heptadecanoic acid, 5 g | sc-215139A | 5 g | $73.00 |