Molecular structure of Estrone 3-sulfate sodium salt, CAS Number: 438-67-5
Estrone 3-sulfate sodium salt (CAS 438-67-5)
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Alternate Names:
Estra-1,3,5(10)-trien-17-one 3-(Sulfooxy) Sodium Salt; Estrone Sulfate Sodium Salt
Application:
Estrone 3-sulfate sodium salt is an estrogen hormone
CAS Number:
438-67-5
Molecular Weight:
372.41
Molecular Formula:
C18H21O5S•Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Estrone 3-Sulfate Sodium Salt, also known as Premarin, has been extensively employed in diverse scientific research fields to investigate the impact of estrogens on several aspects. It has contributed to the understanding of how estrogens influence the development of reproductive organs, the growth of cancer cells, the immune system′s functioning, brain functions, and the cardiovascular system. By binding to estrogen receptors within the body, Estrone 3-Sulfate Sodium Salt triggers a cascade of events. This activation leads to a range of cellular processes such as gene expression regulation, protein synthesis, hormone production, and cell division regulation.
Estrone 3-sulfate sodium salt (CAS 438-67-5) References
- Quantitative and qualitative determination of estrogen sulfates in human urine by liquid chromatography/tandem mass spectrometry using 96-well technology. | Zhang, H. and Henion, J. 1999. Anal Chem. 71: 3955-64. PMID: 10500482
- Identification of a sodium-dependent organic anion transporter from rat adrenal gland. | Geyer, J., et al. 2004. Biochem Biophys Res Commun. 316: 300-6. PMID: 15020217
- A receptor-independent effect of estrone sulfate on the HERG channel. | Kakusaka, S., et al. 2009. J Pharmacol Sci. 109: 152-6. PMID: 19129680
- Impact of carriers in oral absorption: Permeation across Caco-2 cells for the organic anions estrone-3-sulfate and glipizide. | Gram, LK., et al. 2009. Eur J Pharm Sci. 37: 378-86. PMID: 19491029
- Impact of transporters in oral absorption: a case study of in vitro and in vivo organic anion absorption. | Gram, LK., et al. 2009. Mol Pharm. 6: 1457-65. PMID: 19548658
- Multiple Linear Regression Analysis Indicates Association of P-Glycoprotein Substrate or Inhibitor Character with Bitterness Intensity, Measured with a Sensor. | Yano, K., et al. 2015. J Pharm Sci. 104: 2789-94. PMID: 25545612
- Marketplace Analysis of Conjugated Estrogens: Determining the Consistently Present Steroidal Content with LC-MS. | Levy, MJ., et al. 2015. AAPS J. 17: 1438-45. PMID: 26242210
- An ultrasensitive and selective electrochemical sensor for determination of estrone 3-sulfate sodium salt based on molecularly imprinted polymer modified carbon paste electrode. | Song, H., et al. 2017. Anal Bioanal Chem. 409: 6509-6519. PMID: 28889259
- The Impacts of Genistein and Daidzein on Estrogen Conjugations in Human Breast Cancer Cells: A Targeted Metabolomics Approach. | Poschner, S., et al. 2017. Front Pharmacol. 8: 699. PMID: 29051735
- Interaction of soy isoflavones and their main metabolites with hOATP2B1 transporter. | Navrátilová, L., et al. 2018. Naunyn Schmiedebergs Arch Pharmacol. 391: 1063-1071. PMID: 29934673
- Hyperosmolarity stimulates transporter-mediated insertion of estrone sulfate into the plasma membrane, but inhibits the uptake by SLC10A1 (NTCP). | Müller, JP., et al. 2021. Biochem Pharmacol. 186: 114484. PMID: 33617845
- Structural Plasticity Is a Feature of Rheostat Positions in the Human Na+/Taurocholate Cotransporting Polypeptide (NTCP). | Ruggiero, MJ., et al. 2022. Int J Mol Sci. 23: PMID: 35328632
- Mechanistic in vitro studies indicate that the clinical drug-drug interactions between protease inhibitors and rosuvastatin are driven by inhibition of intestinal BCRP and hepatic OATP1B1 with minimal contribution from OATP1B3, NTCP and OAT3. | Elsby, R., et al. 2023. Pharmacol Res Perspect. 11: e01060. PMID: 36811234
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Estrone 3-sulfate sodium salt, 10 mg | sc-207642 | 10 mg | $185.00 | |||
Estrone 3-sulfate sodium salt, 50 mg | sc-207642A | 50 mg | $899.00 |