Molecular structure of D-Luciferin, CAS Number: 2591-17-5
D-Luciferin (CAS 2591-17-5)
See product citations (3)
Alternate Names:
D-Luciferin is also known as Firefly Luciferin.
Application:
D-Luciferin is a chemiluminescent luciferase substrate
CAS Number:
2591-17-5
Molecular Weight:
280.33
Molecular Formula:
C11H8N2O3S2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
D-Luciferin is a chemiluminescent substrate of the bioluminescent enzyme luciferase. D-Luciferin is cell-permeable and emits light upon oxidative decarboxylation in presence of ATP. D-Luciferin and luciferase can be used to assess ATP availability in cellular or biochemical assays.
D-Luciferin (CAS 2591-17-5) References
- Influence of bioluminescence imaging dynamics by D-luciferin uptake and efflux mechanisms. | Zhang, Y., et al. 2012. Mol Imaging. 11: 499-506. PMID: 23084250
- Beyond D-luciferin: expanding the scope of bioluminescence imaging in vivo. | Adams, ST. and Miller, SC. 2014. Curr Opin Chem Biol. 21: 112-20. PMID: 25078002
- Label-Free Cell Phenotypic Identification of D-Luciferin as an Agonist for GPR35. | Hu, H., et al. 2016. Methods Mol Biol. 1461: 3-17. PMID: 27424891
- Luciferin-Regenerating Enzyme Crystal Structure Is Solved but its Function Is Still Unclear. | Hosseinkhani, S., et al. 2017. Photochem Photobiol. 93: 429-435. PMID: 28120440
- Biosynthesis-inspired deracemizative production of d-luciferin by combining luciferase and thioesterase. | Maeda, J., et al. 2017. Biochim Biophys Acta Gen Subj. 1861: 2112-2118. PMID: 28454735
- Organic anion transporter 1 (OAT1/SLC22A6) enhances bioluminescence based on d-luciferin-luciferase reaction in living cells by facilitating the intracellular accumulation of d-luciferin. | Furuya, T., et al. 2018. Biochem Biophys Res Commun. 495: 2152-2157. PMID: 29273507
- Synthesis and quantitative characterization of coumarin-caged D-luciferin. | Kurata, M., et al. 2018. J Photochem Photobiol B. 189: 81-86. PMID: 30317051
- Stability of d-luciferin for bioluminescence to detect gene expression in freely moving mice for long durations. | Nakajima, K., et al. 2021. Luminescence. 36: 94-98. PMID: 32721066
- Luminogenic D-Luciferin Derivatives as OATP1B1 and 1B3 Substrates in No-wash Assays. | Ma, D., et al. 2021. Photochem Photobiol. 97: 1407-1416. PMID: 33948961
- Luciferin Synthesis and Pesticide Detection by Luminescence Enzymatic Cascades. | Watthaisong, P., et al. 2022. Angew Chem Int Ed Engl. 61: e202116908. PMID: 35138676
- Biosynthesis-Inspired Deracemizative Production of D-Luciferin In Vitro by Combining Luciferase and Thioesterase. | Niwa, K. and Kato, DI. 2022. Methods Mol Biol. 2524: 53-58. PMID: 35821462
- A Simple and Rapid Bioluminescence-Based Functional Assay of Organic Anion Transporter 1 as a D-Luciferin Transporter. | Inoue, K., et al. 2022. Methods Mol Biol. 2524: 119-126. PMID: 35821467
- Bioluminescence imaging using d-luciferin and its analogs for visualizing Bdnf expression in living mice; different patterns of bioluminescence signals using distinct luciferase substrates. | Fukuchi, M., et al. 2022. J Biochem. 172: 321-327. PMID: 36047849
Inhibitor of:
β-Galactosidase, and FucU.Activator of:
Luciferase, and SAGE1.Substrate of:
Luciferase.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
D-Luciferin, 25 mg | sc-207478 | 25 mg | $72.00 | |||
D-Luciferin, 100 mg | sc-207478A | 100 mg | $187.00 | |||
D-Luciferin, 1 g | sc-207478B | 1 g | $928.00 |