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Cantharidic acid, an analog of cantharidin (CA), is a potent and selective inhibitor of PP2 (protein phosphatase (PP2A) and PP1 (protein phosphatase 1). PP2A regulates phosphorylation-dephosphorylation events and is found in plants and mammalian tissues. Studies show that it can cause biochemical changes in the mouse liver. Both okadaic acid (sc-3513), also a PP2A inhibitor, and cantharidic acid have been demonstrated to elevate levels of microtubule-bound phospho-53 in the breast cancer cell line, MCF7. Cantharidic acid does not inhibit PP2B or PP2C.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cantharidic Acid, 10 mg | sc-201323 | 10 mg | $102.00 | |||
Cantharidic Acid, 50 mg | sc-201323A | 50 mg | $346.00 |