Date published: 2025-10-12

1-800-457-3801

SCBT Portrait Logo
Seach Input

Aminoguanidine sulfate (CAS 1068-42-4)

0.0(0)
Write a reviewAsk a question

CAS Number:
1068-42-4
Molecular Weight:
172.2
Molecular Formula:
CH6N4.H2O4S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

Aminoguanidine sulfate is a compound that functions as an inhibitor of advanced glycation end products (AGEs) formation. It acts by trapping the reactive carbonyl species that are involved in the formation of AGEs, preventing the cross-linking of proteins and the subsequent tissue damage. Aminoguanidine sulfate works by binding to the carbonyl groups of reducing sugars and reactive dicarbonyl compounds, thereby inhibiting the formation of AGEs. Aminoguanidine Sulfate′s mechanism of action involves interfering with the glycation process.


Aminoguanidine sulfate (CAS 1068-42-4) References

  1. Dual role for nitric oxide in paracoccidioidomycosis: essential for resistance, but overproduction associated with susceptibility.  |  Nascimento, FR., et al. 2002. J Immunol. 168: 4593-600. PMID: 11971007
  2. Effect of a histaminase in hibitor (aminoguanidine sulfate) on pregnant and non-pregnant rats.  |  HOFFMAN, DB. and POLLACK, E. 1961. Am J Obstet Gynecol. 82: 144-6. PMID: 13715007
  3. The protective effect of an antihistaminic on the toxemia-like changes caused by aminoguanidine sulfate in pregnant rats.  |  HOFFMAN, DB. and POLLACK, E. 1963. Am J Obstet Gynecol. 86: 260-3. PMID: 13963919
  4. Partial destruction and recovery of the liver of chick embryos followig injection of aminoguanidine sulfate into the yolk.  |  NOSAL, RA. and WATTERSON, RL. 1959. J Morphol. 105: 529-67. PMID: 14427695
  5. [Effects of aminoguanidine sulfate on hepatic and blood levels of histamine after partial hepatectomy in rats].  |  Moulinoux, JP., et al. 1977. C R Seances Soc Biol Fil. 171: 1288-92. PMID: 148960
  6. The role of nitric oxide in resistance to P. aeruginosa ocular infection.  |  Hazlett, LD., et al. 2005. Ocul Immunol Inflamm. 13: 279-88. PMID: 16159718
  7. Activity of liver fructose diphosphatase from chick embryos treated with aminoguanidine sulfate.  |  Han, PF., et al. 1975. Poult Sci. 54: 746-50. PMID: 168565
  8. Histological studies on developing chick embryos treated with aminoguanidine sulfate.  |  Sugiyama, T., et al. 1985. J Toxicol Sci. 10: 143-53. PMID: 4032502
  9. [Effect of aminoguanidine sulfate and related compounds on chick embryos].  |  Sugiyama, T., et al. 1985. Yakugaku Zasshi. 105: 878-85. PMID: 4093871
  10. [Action of aminoguanidine sulfate on the differentiation in vitro of myocardial cells].  |  Le Douarin, N., et al. 1967. C R Seances Soc Biol Fil. 161: 910-3. PMID: 4229517
  11. [Effect of aminoguanidine sulfate on the hepatic level of polyamines after partial hepatectomy in rats].  |  Moulinoux, JP., et al. 1981. C R Seances Soc Biol Fil. 175: 828-34. PMID: 6459827
  12. N-(3-aminopropyl)pyrrolidin-2-one: a physiological excretory product deriving from spermidine.  |  Seiler, N. and Knödgen, B. 1983. Int J Biochem. 15: 907-15. PMID: 6884567
  13. Effects of the sites of injection of aminoguanidine sulfate on developing eggs.  |  Sugiyama, T., et al. 1982. J Pharmacobiodyn. 5: 1-12. PMID: 7077516
  14. Effects of aminoguanidine sulfate on the incorporation of amino acids and bases into chick embryonic liver and body.  |  Sugiyama, T., et al. 1980. J Pharmacobiodyn. 3: 649-58. PMID: 7277180
  15. Polyamine depletion-mediated effects on murine odontogenesis are dependent on tooth developmental stage and culture conditions.  |  Gritli-Linde, A., et al. 1995. Int J Dev Biol. 39: 383-93. PMID: 7669549

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Aminoguanidine sulfate, 100 g

sc-268510
100 g
$103.00