4-Methylcatechol (CAS 452-86-8)
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4-Methylcatechol is a chemical compound that functions as a substrate in various enzymatic reactions. It acts as a precursor in the synthesis of agrochemicals, and organic compounds. Its mechanism of action involves participating in oxidation and reduction reactions, leading to the formation of specific intermediates and final products. 4-Methylcatechol interacts with enzymes and other chemical reagents to facilitate the production of desired compounds in pathways. Its presence in experimental setups enables the controlled formation of specific chemical bonds and functional groups, contributing to the success of the process. At the molecular level, 4-Methylcatechol undergoes specific chemical transformations, leading to the generation of key intermediates that are for the synthesis of target molecules. Its role in experimental applications involves serving as a building block for the creation of diverse chemical structures, supporting the advancement in various fields.
4-Methylcatechol (CAS 452-86-8) References
- 4-methylcatechol increases brain-derived neurotrophic factor content and mRNA expression in cultured brain cells and in rat brain in vivo. | Nitta, A., et al. 1999. J Pharmacol Exp Ther. 291: 1276-83. PMID: 10565852
- 4-Methylcatechol-induced heme oxygenase-1 exerts a protective effect against oxidative stress in cultured neural stem/progenitor cells via PI3 kinase/Akt pathway. | Furukawa, Y., et al. 2010. Biomed Res. 31: 45-52. PMID: 20203419
- 4-Methylcatechol-induced oxidative stress induces intrinsic apoptotic pathway in metastatic melanoma cells. | Payton, F., et al. 2011. Biochem Pharmacol. 81: 1211-8. PMID: 21419106
- 4-methylcatechol inhibits protein oxidation in meat but not disulfide formation. | Jongberg, S., et al. 2011. J Agric Food Chem. 59: 10329-35. PMID: 21861533
- Intracerebroventricular 4-methylcatechol (4-MC) ameliorates chronic pain associated with depression-like behavior via induction of brain-derived neurotrophic factor (BDNF). | Fukuhara, K., et al. 2012. Cell Mol Neurobiol. 32: 971-7. PMID: 22198556
- 4-Methylcatechol prevents derangements of brain-derived neurotrophic factor and TrkB-related signaling in anterior cingulate cortex in chronic pain with depression-like behavior. | Ishikawa, K., et al. 2014. Neuroreport. 25: 226-32. PMID: 24518228
- 4-Methylcatechol-induced cell damage in TM4 Sertoli cells. | Li, C., et al. 2015. Cell Biol Int. 39: 770-4. PMID: 25639863
- 4-Methylcatechol inhibits cell growth and testosterone production in TM3 Leydig cells by reducing mitochondrial activity. | Li, CJ., et al. 2017. Andrologia. 49: PMID: 27147129
- 4-Methylcatechol stimulates apoptosis and reduces insulin secretion by decreasing betacellulin and inhibin beta-A in INS-1 beta-cells. | Karatug Kacar, A., et al. 2018. Hum Exp Toxicol. 37: 1123-1130. PMID: 29473434
- 4-Methylcatechol prevents streptozotocin-induced acute kidney injury through modulating NGF/TrkA and ROS-related Akt/GSK3β/β-catenin pathways. | Gezginci-Oktayoglu, S., et al. 2018. Int Immunopharmacol. 64: 52-59. PMID: 30145470
- 4-Methylcatechol, a Flavonoid Metabolite with Potent Antiplatelet Effects. | Applová, L., et al. 2019. Mol Nutr Food Res. 63: e1900261. PMID: 31343835
- Covalent bonding of 4-methylcatechol to β-lactoglobulin results in the release of cysteine-4-methylcatechol adducts after in vitro digestion. | Waqar, K., et al. 2022. Food Chem. 397: 133775. PMID: 35917780
- The Antiplatelet Effect of 4-Methylcatechol in a Real Population Sample and Determination of the Mechanism of Action. | Hrubša, M., et al. 2022. Nutrients. 14: PMID: 36432485
- Pharmacology-based molecular docking of 4-methylcatechol and its role in RANKL-mediated ROS/Keap1/Nrf2 signalling axis and osteoclastogenesis. | Xu, Y., et al. 2023. Biomed Pharmacother. 159: 114101. PMID: 36640671
- The Effect of 4-Methylcatechol on Platelets in Familial Hypercholesterolemic Patients Treated with Lipid Apheresis and/or Proprotein Convertase Subtilisin Kexin 9 Monoclonal Antibodies. | Konečný, L., et al. 2023. Nutrients. 15: PMID: 37111061
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
4-Methylcatechol, 25 g | sc-356905 | 25 g | $33.00 | |||
4-Methylcatechol, 100 g | sc-356905A | 100 g | $100.00 |