Date published: 2025-9-18

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1-(p-Tolyl)ethanol (CAS 536-50-5)

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CAS Number:
536-50-5
Molecular Weight:
136.19
Molecular Formula:
C9H12O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1-(p-Tolyl)ethanol, also known as para-methylbenzyl alcohol, has garnered significant interest in scientific research due to its versatile applications across various fields. In organic chemistry, it serves as a crucial starting material for the synthesis of diverse compounds, including fragrances, flavors, and pharmaceutical intermediates. Its mechanism of action often involves nucleophilic substitution reactions, where the hydroxyl group undergoes substitution reactions with various electrophiles, leading to the formation of diverse functionalized products. In addition, 1-(p-Tolyl)ethanol has been extensively investigated in the field of material science for its potential use as a precursor in the synthesis of polymers, coatings, and functionalized surfaces. Research efforts have focused on optimizing synthetic routes to produce high-purity 1-(p-Tolyl)ethanol and exploring its reactivity towards different functionalization reactions to tailor its properties for specific applications. Furthermore, studies have explored its role as a chiral auxiliary in asymmetric synthesis, leveraging its stereochemical properties to enable the synthesis of enantiomerically enriched compounds with high levels of stereocontrol. Overall, the broad utility and reactivity of 1-(p-Tolyl)ethanol make it a valuable tool in organic synthesis and material science research, with ongoing investigations aimed at expanding its applications and enhancing synthetic methodologies.


1-(p-Tolyl)ethanol (CAS 536-50-5) References

  1. Effect of modification of thyroid function on cholesterol 7 alpha-hydroxylation in rat liver.  |  Takeuchi, N., et al. 1975. Biochem J. 148: 499-503. PMID: 1200990
  2. Combined ruthenium(II) and lipase catalysis for efficient dynamic kinetic resolution of secondary alcohols. Insight into the racemization mechanism.  |  Martín-Matute, B., et al. 2005. J Am Chem Soc. 127: 8817-25. PMID: 15954789
  3. Alkylation of Sulfonamides with Trichloroacetimidates under Thermal Conditions.  |  Wallach, DR. and Chisholm, JD. 2016. J Org Chem. 81: 8035-42. PMID: 27487402
  4. Direct Selective Oxidative Functionalization of C-H Bonds with H₂O₂: Mn-Aminopyridine Complexes Challenge the Dominance of Non-Heme Fe Catalysts.  |  Ottenbacher, RV., et al. 2016. Molecules. 21: PMID: 27809257
  5. Iron-Catalyzed Selective Etherification and Transetherification Reactions Using Alcohols.  |  Sahoo, PK., et al. 2018. ACS Omega. 3: 124-136. PMID: 31457881
  6. Catalytic Hydroboration of Aldehydes, Ketones, and Alkenes Using Potassium Carbonate: A Small Key to Big Transformation.  |  Ma, DH., et al. 2019. ACS Omega. 4: 15893-15903. PMID: 31592459
  7. Manganese(I)-Catalyzed β-Methylation of Alcohols Using Methanol as C1 Source.  |  Kaithal, A., et al. 2020. Angew Chem Int Ed Engl. 59: 215-220. PMID: 31651071
  8. Functionalized Magnetic Nanoparticles as Catalysts for Enantioselective Henry Reaction.  |  Sappino, C., et al. 2019. ACS Omega. 4: 21809-21817. PMID: 31891058
  9. A nickel phosphide nanoalloy catalyst for the C-3 alkylation of oxindoles with alcohols.  |  Fujita, S., et al. 2021. Sci Rep. 11: 10673. PMID: 34021187
  10. Preparation and Asymmetric Induction Evaluation of the First Ephedrine-Based Ligands Immobilized on Magnetic Nanoparticles.  |  Primitivo, L., et al. 2021. ACS Omega. 6: 35641-35648. PMID: 34984295

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1-(p-Tolyl)ethanol, 100 ml

sc-222624
100 ml
$224.00