Date published: 2026-5-11

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Zanubrutinib (CAS 1691249-45-2)

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Datasheets
Alternate Names:
(7S)-4,5,6,7-tetrahydro-7-[1-(1-oxo-2-propen-1-yl)-4-piperidinyl]-2-(4-phenoxyphenyl)-pyrazolo[1,5-a]pyrimidine-3-carboxamide, BGB-3111
CAS Number:
1691249-45-2
Molecular Weight:
471.6
Molecular Formula:
C27H29N5O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

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Zanubrutinib (CAS 1691249-45-2) References

  1. Efficacy and safety of new-generation Bruton tyrosine kinase inhibitors in chronic lymphocytic leukemia/small lymphocytic lymphoma: a systematic review and meta-analysis.  |  Yin, S., et al. 2024. Ann Hematol. 103: 2231-2244. PMID: 37843620
  2. A prospective study of zanubrutinib, a Bruton tyrosine kinase inhibitor, in relapsed/refractory idiopathic multicentric Castleman disease.  |  Zhang, L., et al. 2024. Int J Hematol. 119: 631-637. PMID: 38546960
  3. New Means and Challenges in the Targeting of BTK.  |  Nawaratne, V., et al. 2024. Clin Cancer Res. 30: 2333-2341. PMID: 38578606
  4. Development of combination therapies with BTK inhibitors and dasatinib to treat CNS-infiltrating E2A-PBX1+/preBCR+ ALL.  |  Gentile, G., et al. 2024. Blood Adv. 8: 2846-2860. PMID: 38598725
  5. An indirect comparison of acalabrutinib with and without obinutuzumab vs zanubrutinib in treatment-naive CLL.  |  Kittai, AS., et al. 2024. Blood Adv. 8: 2861-2869. PMID: 38598745
  6. Evaluating zanubrutinib for the treatment of adults with chronic lymphocytic leukemia or small lymphocytic lymphoma.  |  Javidi-Sharifi, N. and Brown, JR. 2024. Expert Rev Hematol. 17: 201-210. PMID: 38784995
  7. Bruton's tyrosine kinase inhibitors in primary central nervous system lymphoma: New hopes on the horizon.  |  Lino-Silva, LS., et al. 2024. World J Clin Oncol. 15: 587-590. PMID: 38835851
  8. Strategies for overcoming resistance to Bruton's tyrosine kinase inhibitor zanubrutinib.  |  Dostálová, H. and Kryštof, V. 2024. Hematol Oncol. 42: e3294. PMID: 38847437
  9. Current Approaches and Novel New Agents in the Treatment of Chronic Lymphocytic Leukemia.  |  Cheson, BD. and Sharman, JP. 2024. JCO Oncol Pract. OP2300770. PMID: 38848511
  10. Integrative bioinformatics approach for identifying key genes and potential therapeutic targets in the concurrent manifestation of hypertrophic cardiomyopathy and pulmonary hypertension.  |  Zheng, X., et al. 2024. J Thorac Dis. 16: 3152-3169. PMID: 38883633
  11. Improved efficacy and safety of zanubrutinib versus ibrutinib in patients with relapsed/refractory chronic lymphocytic leukemia (R/R CLL) in China: a subgroup of ALPINE.  |  Zhou, K., et al. 2024. Ann Hematol.. PMID: 38888616
  12. Covalent Bruton's Tyrosine Kinase Inhibitors in Chronic Lymphocytic Leukemia.  |  Alsouqi, A. and Woyach, JA. 2024. Clin Lymphoma Myeloma Leuk.. PMID: 38897870
  13. A rare case of Richter transformation with breast involvement: A case report and literature review.  |  Wang, W., et al. 2024. Open Life Sci. 19: 20220889. PMID: 38911930

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Zanubrutinib, 5 mg

sc-507434
5 mg
$360.00