Sulfo-NONOate disodium salt CAS: 61142-90-3
MF: N2O5S•2Na
MW: 186.07
A control compound for NONOate studies.

Sulfo-NONOate disodium salt (CAS 61142-90-3)

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Aplicação Sulfo-NONOate disodium salt is a control compound for NONOate studies
Numero VAT: 61142-90-3
Peso Molecular: 186.07
Separar por Funcao: N2O5S•2Na
Para uso em exclusivo em pesquisa. Não se destina a uso em diagnostico e tratamento.
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Sulfo-NONOate disodium salt is the disodium salt of N-nitrosohydroxylamine-N-sulfonic acid, decomposing in aqueous solution to release nitrous oxide (N2O) with a half-life of ~32 min (22-25°C for diammonium salt). As Sulfo-NONOate disodium salt releases N2O without releasing NO, it is useful as a negative control for studies employing the NO release from NONOates.


Referencias

1. Maragos, C M., et al., 1991. Complexes of .NO with nucleophiles as agents for the controlled biological release of nitric oxide. Vasorelaxant effects. Journal of medicinal chemistry. 34(11): 3242-7. PMID: 1956043
2. Maragos, C M., et al., 1993. Nitric oxide/nucleophile complexes inhibit the in vitro proliferation of A375 melanoma cells via nitric oxide release. Cancer research. 53(3): 564-8. PMID: 8425188
3. Keefer, L K., et al., 1996. "NONOates" (1-substituted diazen-1-ium-1,2-diolates) as nitric oxide donors: convenient nitric oxide dosage forms. Methods in enzymology. 268(): 281-93. PMID: 8782594

Aparência :
Crystalline
Estado físico :
Solid
envie :
soluble in water
Manutencao :
Store at -80° C
Para uso em exclusivo em pesquisa. Não se destina a uso em diagnostico e tratamento.
PubChem CID :
SMILES :
C(N=O)([O-])S(=O)(=O)[O-].[Na+].[Na+]

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