LINKS RÁPIDOS
SUGT1 (Suppressor of G2 allele of Skp1 p19 homolog, S. cerevisiae), also known as SGT1, is a homolog of the yeast protein Sgt1, a regulator of the cell cycle that is essential for G1/S and G2/M transitions. SUGT1 is a highly soluble protein and shares 26% overall amino acid identity and 30% overall similarity with its yeast counterpart. Localizing to the nucleus and cytoplasm, SUGT1 contains a CS domain, a SGS domain, a p23 domain and three tetratricopeptide repeats (TPR). The function of SUGT1 is conserved across eukaryotes. SUGT1 associates with Skp1 p19 and CUL1, subunits of the SCF (Skp1-Cullin-F-box) ubiquitin ligase complex, and is believed to play a role in protein degradation. In addition, SUGT1 is required for the assembly of kinetochores and functions as a co-chaperone for HSP 90. An additional isoform, SUGT1B (also known as SGT1B), exists for SUGT1 due to alternative splicing events.
Informacoes sobre ordens
Nome do Produto | Numero de Catalogo | UNID | Preco | Qde | FAVORITOS | |
SUGT1 Anticorpo (YQ-R3) | sc-81822 | 100 µg/ml | $333.00 |