ChemCruz™ Produtos químicos
SGK Inibidores para análise funcional de respostas celulares a SGK
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
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SGK2 Antibody (3Q-2) is a high quality monoclonal SGK2 antibody (also designated SGK2 antibody) suitable for the detection of the SGK2 protein of mouse, rat and human origin. SGK2 Antibody (3Q-2) is available as the non-conjugated anti-SGK2 antibody. The serum- and glucocorticoid-regulated kinases (SGKs) include SGK1, SGK2 and SGK3 and are members of the serine/threonine protein kinase family. SGKs play an important role in activating certain potassium, sodium and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability and renal sodium excretion. The SGKs display structural and sequence similarity to the PKB/Akt family except for the absence of a Pleckstrin homology (PH) domain. The SGKs are also downstream targets of PI 3-kinase-stimulated growth factor signaling. They can all phosphorylate NEDD4-1, which subsequently activates various channels and transporters including ENaC, KV1.3 or EAAT1. Aldosterone induces the expression of SGK1, but not SGK2 or SGK3. SGK3 is ubiquitously expressed, but SGK2 only shows significant levels of expression in liver, kidney and pancreas.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.