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PP5 Antibody (F-12): sc-271817

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Datasheets
  • PP5 Antibody (F-12) is a mouse monoclonal IgG3 κ provided at 200 µg/ml
  • specific for an epitope mapping between amino acids 463-490 at the C-terminus of PP5 of human origin
  • recommended for detection of PP5 of mouse, rat and human origin by WB, IP, IF and ELISA
  • m-IgG3 BP-HRP is the preferred secondary detection reagent for PP5 Antibody (F-12) for WB applications. This reagent is now offered in a bundle with PP5 Antibody (F-12) (see ordering information below).
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    PP5 Antibody (F-12) is a mouse monoclonal IgG3 antibody that detects PP5 in mouse, rat, and human samples through western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). PP5, also known as Protein phosphatase T, plays a crucial role in cellular regulation by dephosphorylating serine residues on various substrates, including skeletal muscle phosphorylase and histone H1, which are vital for processes such as mitosis and RNA biogenesis. PP5 (F-12) antibody targets a protein predominantly located in the nucleus, where PP5 is involved in the regulation of gene expression and cell cycle progression, making PP5 essential for maintaining cellular homeostasis and proper cell division. The unique structure of PP5, which includes a catalytic domain and regulatory elements, allows PP5 to interact with specific proteins like CDC16 and CDC27, further emphasizing PP5′s importance in the intricate network of cellular signaling pathways. Anti-PP5 antibody (F-12) enables researchers to gain valuable insights into the functional dynamics of PP5 and its implications in various biological processes and diseases.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    PP5 Antibody (F-12)

    sc-271817
    200 µg/ml
    $322.00

    PP5 Antibody (F-12): m-IgG3 BP-HRP Bundle

    sc-550410
    200 µg Ab; 40 µg BP
    $361.00

    PP5 (F-12) Neutralizing Peptide

    sc-271817 P
    100 µg/0.5 ml
    $69.00

    What application is the blocking peptide sc-271817 P appropriate for?

    Asked by: TinTin
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Answered by: Technical Support
    Date published: 2017-02-27
    • y_2026, m_5, d_21, h_10CST
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    Rated 5 out of 5 by from Excellent immunofluorescence nuclear andExcellent immunofluorescence nuclear and cytoplasmic staining in formalin-fixed HepG2 cells. -SCBT QC
    Date published: 2015-05-16
    Rated 5 out of 5 by from Nice Western Blot data of PP5 expression in HeLaNice Western Blot data of PP5 expression in HeLa, Jurkat, PC-12 and A-431 whole cell lysates. -SCBT QC
    Date published: 2014-03-05
    • y_2026, m_5, d_20, h_12
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    PP5 Antibody (F-12) is rated 5.0 out of 5 by 2.
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