plakophilin 3 Antibody (E612B11F8): sc-73578
- plakophilin 3 Antibody (E612B11F8) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- raised against amino acids 779-793 of plakophilin 3 of human origin
- recommended for detection of plakophilin 3 of mouse, rat, human, Xenopus and canine origin by WB, IP and IF; non cross-reactive with any other plakophilin or armadillo protein
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for plakophilin 3 Antibody (E612B11F8) for WB applications. This reagent is now offered in a bundle with plakophilin 3 Antibody (E612B11F8) (see ordering information below).
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Plakophilin 3 Antibody (E612B11F8) is a mouse monoclonal IgG2a antibody that detects plakophilin 3 in mouse, rat, human, Xenopus, and canine samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Plakophilin 3 is a 797 amino acid protein characterized by eight arm-repeat domains, which are crucial for linking cadherins to cytoskeletal intermediate filaments, thereby facilitating cell adhesion and maintaining tissue integrity. Plakophilin 3 is predominantly localized to desmosomes, specialized cell-cell junctions essential for the structural stability of tissues subjected to mechanical stress, such as the skin and heart. Anti-plakophilin 3 antibody (E612B11F8) helps researchers study desmosome-dependent adhesion and signaling pathways, which are vital for cellular communication and tissue homeostasis. Plakophilin 3 has been implicated in lung carcinogenesis, with up-regulation serving as a significant marker for cancer progression, highlighting potential as a prognostic indicator and therapeutic target in lung cancer treatment. Plakophilin 3 monoclonal antibody (E612B11F8) serves as an invaluable tool for investigating plakophilin 3 in both normal physiology and disease states.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
plakophilin 3 Antibody (E612B11F8) | sc-73578 | 200 µg/ml | $322.00 | |||
plakophilin 3 Antibody (E612B11F8): m-IgG Fc BP-HRP Bundle | sc-539499 | 200 µg Ab; 10 µg BP | $361.00 |