Nkx-2.5 Antibody (F-2): sc-365207
- Nkx-2.5 Antibody (F-2) is a mouse monoclonal IgG1 λ, cited in 2 publications, provided at 200 µg/ml
- raised against amino acids 24-137 mapping near the N-terminus of Nkx-2.5 of human origin
- recommended for detection of Nkx-2.5 of human origin by WB, IP, IF and ELISA
- TransCruz reagent for ChIP application (sc-365207 X, 200 µg/0.1 ml)
- See Nkx-2.5 (A-3): sc-376565 for Nkx-2.5 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgGλ BP-HRP (mouse IgGλ binding protein-HRP) is the preferred secondary detection reagent for Nkx-2.5 Antibody (F-2) for WB applications. This reagent is now offered in a bundle with Nkx-2.5 Antibody (F-2) (see ordering information below). For additional m-IgGλ BP conjugates see our complete list of Mouse IgG Binding Proteins.
Nkx-2.5 Antibody (F-2) is a mouse monoclonal IgG1 antibody that detects Nkx-2.5 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Nkx-2.5, also known as cardiac specific homeobox protein (Csx), plays a crucial role in cardiac development as a transcription factor that regulates the expression of genes essential for heart formation and function. Nkx-2.5 is primarily located in the nucleus, where DNA binding influences the transcription of target genes involved in cardiomyocyte differentiation and cardiac morphogenesis. Proper localization of Nkx-2.5 ensures appropriate gene activation during embryonic development, particularly during critical stages of heart formation. Disruptions in Nkx-2.5 expression or function can lead to severe developmental issues, including congenital heart defects and cardiovascular anomalies. Anti-Nkx-2.5 antibody (F-2) serves as an invaluable tool for researchers studying cardiac development and related pathologies, providing insights into molecular mechanisms underlying heart formation and function.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Nkx-2.5 Antibody (F-2) | sc-365207 | 200 µg/ml | $322.00 | |||
Nkx-2.5 Antibody (F-2): m-IgGλ BP-HRP Bundle | sc-522163 | 200 µg Ab, 40 µg BP | $361.00 | |||
Nkx-2.5 Antibody (F-2) X | sc-365207 X | 200 µg/0.1 ml | $322.00 |