Anti-MTHFD1 Anticorpo A-8é um anticorpo monoclonal produzido em camundongo IgG1 κ MTHFD1 anticorpo, citado em 3 publicações, fornecido em 200 µg/ml
produzido contra aminoácidos 1-120 mapeamento no N-terminus de MTHFD1 of human origem
MTHFD1 Anticorpo (A-8) é recomendado para a detecção de MTHFD1 of human origin by WB, IP, IF, IHC(P) and ELISA
Anti-MTHFD1 Antibody (A-8) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Entre em contato conosco e receba GRATUITAMENTE um amostra de 10 µg de MTHFD1 (A-8): sc-271412.
m-IgGκ BP-HRP is the preferred secondary detection reagent for MTHFD1 Antibody (A-8) for WB and IHC(P) applications. This reagent is now offered in a bundle with MTHFD1 Antibody (A-8) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
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Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
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Labware ships FedEx Ground free of charge to the contiguous US
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MTHFD1 Antibody (A-8) is a high quality monoclonal MTHFD1 antibody (also designated MTHFD1 antibody) suitable for the detection of the MTHFD1 protein of human origin. MTHFD1 Antibody (A-8) is available as both the non-conjugated anti-MTHFD1 antibody form, as well as multiple conjugated forms of anti-MTHFD1 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Methylenetetrahydrofolate dehydrogenase 1 (MTHFD1) is a 935-amino acid, folate-dependent protein that is responsible for the consecutive interconversion of tetrahydrofolate derivatives which drive the synthesis of purine, methionine, and thymidylate. The cytosolic MRHFD1 contains three subunits, 5,10-methylenetetrahydrofolate dehydrogenase, 5,10-methenyltetrahydrofolate cyclohydrolase, and 10-formyltetrahydrofolate synthetase, each with distinct activities. MTHFD1 functions as a homodimer consisting of two major domains, an N-terminal containing the dehydrogenase and cyclohydrolase activities and a larger synthetase domain in the C-terminus. Mutations in the MTHFD1 gene in pregnant women are associated with an increased risk of giving birth to a child with a neural tube defect, along with a possible risk of decreased embryo survival. MTHFD1 also plays a role in migraine development, since folate metabolism is involved in migraine pathophysiology, mainly in migraine with aura.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
To place an order using RMB or to ship to mainland China, please visit www.scbio.cn