Date published: 2025-10-28

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MEG sodium succinate (CAS 1190-74-5 (non-salt))

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Nomes alternativos:
Mercaptoethylguanidine sodium succinate
Aplicacao:
MEG sodium succinate é um inibidor da NOS2 (iNOS) e um sequestrador de peroxinitritos
Numero VAT:
1190-74-5 (non-salt)
Peso Molecular:
259.26
Separar por Funcao:
C3H10N3S•C4H4O4Na
Para uso em exclusivo em pesquisa. Não se destina a uso em diagnostico e tratamento.
* Refere-se a Certificado de Análise para data especifica de lotes (incluindo-se o conteúdo de agua).

LINKS RÁPIDOS

O succinato sódico de MEG inibe a NOS2 (iNOS). O succinato sódico de MEG é um eliminador de peroxinitritos.


MEG sodium succinate (CAS 1190-74-5 (non-salt)) Referencias

Spontaneous rearrangement of aminoalkylisothioureas into mercaptoalkylguanidines, a novel class of nitric oxide synthase inhibitors with selectivity towards the inducible isoform: G.J. Southan, et al.; Br. J. Pharmacol. 117, 619 (1996) The inhibitory effects of mercaptoalkylguanidines on cyclo-oxygenase activity: B. Zingarelli, et al.; Br. J. Pharmacol. 120, 357 (1997) Mercaptoethylguanidine and guanidine inhibitors of nitric-oxide synthase react with peroxynitrite and protect against peroxynitrite-induced oxidative damage: C. Szabó, et al.; J. Biol. Chem. 272, 9030 (1997) ; Full Text Antiinflammatory effects of mercaptoethylguanidine, a combined inhibitor of nitric oxide synthase and peroxynitrite scavenger, in carrageenan-induced models of inflammation: S. Cuzzocrea, et al.; Free Radic. Biol. Med. 24, 450 (1998) Protective effects of MEG, a selective inhibitor of inducible nitric oxide synthase, in ligature-induced periodontitis in the rat [published erratum appears in Br. J. Pharmacol. 123, 741 (1998)]: Z. Lohinai, et al.; Br. J. Pharmacol. 123, 353 (1998) Mercaptoethylguanidine, a combined inhibitor of nitric oxide synthase and peroxynitrite scavenger, reduces trinitrobenzene sulfonic acid-induced colonic damage in rats: B. Zingarelli, et al.; J. Pharmacol. Exp. Ther. 287, 1048 (1998) Modulation of peroxynitrite- and hypochlorous acid-induced inactivation of alpha1-antiproteinase by mercaptoethylguanidine: M. Whiteman, et al.; Br. J. Pharmacol. 126, 1646 (1999)

Informacoes sobre ordens

Nome do ProdutoNumero de CatalogoUNIDPrecoQdeFAVORITOS

MEG sodium succinate, 10 mg

sc-221879
10 mg
$200.00