Inosine-5′-monophosphate disodium salt octahydrate (CAS 20813-76-7)

Inosine-5′-monophosphate disodium salt octahydrate is a stable, water-soluble form of IMP, which is a key purine nucleotide involved in the synthesis of RNA and DNA. This salt enhances the bioavailability of IMP in aqueous solutions, making it particularly useful in studies related to cellular metabolism and energy balance. It plays a central role in the purine nucleotide cycle, which is vital for the regeneration of ATP in muscle tissues. In cellular systems, IMP is involved in signaling pathways that regulate cell growth and differentiation, particularly in muscle development and repair. It serves as a precursor in the de novo synthesis of adenine and guanine nucleotides, which are essential for cellular replication and transcription processes. The use of IMP in cell culture media can help in studying various aspects of cellular physiology, including nucleotide turnover, energy metabolism, and the effects of metabolic stress on cell viability. Its role in modulating cellular energy states also makes it a tool for investigating the metabolic shifts that occur in cancerous cells versus normal cells.