IAP Antibody (AP-7/6/7): sc-53334

IAP Antibody (AP-7/6/7) is a mouse monoclonal IgG1 antibody that detects intestinal alkaline phosphatase (IAP) in bovine samples through immunofluorescence (IF) applications. Anti-IAP antibody (AP-7/6/7) recognizes a brush-border enzyme that increases significantly during small intestinal epithelial cell differentiation. IAP plays an essential role in limiting fat absorption and participates in trans-cellular transport and chylomicron formation, which are critical for lipid metabolism. IAP functions optimally at high pH levels, removing phosphate groups from proteins and the 5′ ends of DNA and RNA, thereby influencing various biochemical pathways. IAP expression is notably present in tissues such as the liver, bile ducts, placenta, and bone, with expression levels serving as potential biomarkers for various conditions, including bone and liver diseases. Serum IAP levels vary among different ABO blood groups, with individuals of blood group O or B showing higher prevalence, potentially affecting fatty acid metabolism. IAP monoclonal antibody (AP-7/6/7) serves as a valuable tool for researchers studying this enzyme′s roles in bovine physiology and pathology.

The preferred TNAP antibody is TNAP Antibody (F-4): sc-166261.