Anti-FBXO7 Anticorpo E-8é um anticorpo monoclonal produzido em camundongo IgG1 κ FBXO7 anticorpo, citado em 4 publicações, fornecido em 200 µg/ml
específico para um epítopo mapeado entre os aminoácidos 427-461 dentro de uma região interna de FBXO7 de human origem
Anti-FBXO7 Anticorpo (E-8) é recomendado para a detecção de FBXO7 de mouse, rat e human origem em WB, IP, IF e ELISA
Anti-FBXO7 Antibody (E-8) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Entre em contato conosco e receba GRATUITAMENTE um amostra de 10 µg de FBXO7 (E-8): sc-271763.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
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Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
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FBXO7 Antibody (E-8) is a high quality monoclonal FBXO7 antibody (also designated FBX7 antibody) suitable for the detection of the FBXO7 protein of mouse, rat and human origin. FBXO7 Antibody (E-8) is available as both the non-conjugated anti-FBXO7 antibody form, as well as multiple conjugated forms of anti-FBXO7 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular processes (including the cell cycle, immune responses, signaling cascades and developmental events) through the targeting of proteins, such as cyclins, cyclin-dependent kinase inhibitors, IκB-α and β-catenin, for proteasomal degradation. FBXO7 (F-box protein 7), also known as FBX, FBX7 or PKPS, is a 522 amino acid protein that contains one F-box domain and functions as a component of the SCF complex. Defects in the gene encoding FBXO7 are associated with parkinsonian-pyramidal syndrome (PKPS), a hypokinetic rigid disorder that exhibits Parkinsonian and pyramidal-associated symptoms.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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