Anti-FBXO11 Anticorpo E-9é um anticorpo monoclonal produzido em camundongo IgG2b (kappa light chain) FBXO11 anticorpo fornecido em 200 µg/ml
específico para um epítopo mapeado entre os aminoácidos 90-109 no N-terminus de FBXO11 de human origem
FBXO11 Anticorpo (E-9) é recomendado para a detecção de FBXO11 de mouse, rat, human e de origem WB, IP, IF, IHC(P) e ELISA; Reage também com outras espécies, incluindo and equine, canine, bovine, porcine and avian
Anti-FBXO11 Antibody (E-9) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Entre em contato conosco e receba GRATUITAMENTE um amostra de 10 µg de FBXO11 (E-9): sc-393229.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
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FBXO11 Antibody (E-9) is a high quality monoclonal FBXO11 antibody (also designated FBX11 antibody or VIT-1 antibody) suitable for the detection of the FBXO11 protein of mouse, rat and human origin. FBXO11 Antibody (E-9) is available as both the non-conjugated anti-FBXO11 antibody form, as well as multiple conjugated forms of anti-FBXO11 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular processes (including the cell cycle, immune responses, signaling cascades and developmental events) through the targeting of proteins, such as cyclins, cyclin-dependent kinase inhibitors, IκB-α and β-catenin, for proteasomal degradation. FBXO11 (F-box only protein 11), also known as VIT1 (Vitiligo-associated protein 1), is a 927 amino acid nuclear protein that contains one UBR-type zinc finger, one F-box domain and 19 PbH1 repeats. Involved in protein ubiquitination, FBXO11 functions as a substrate recognition component of the SCF complex and is thought to bind to and inhibit the transcriptional activity of p53. Reduced expression of FBXO11 is associated with vitiligo, a disease characterized by progressive skin depigmentation. Multiple isoforms of FBXO11 exist due to alternative splicing events.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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