Anti-Dyskerin Anticorpo H-3é um anticorpo monoclonal produzido em camundongo IgG2a κ Dyskerin anticorpo, citado em 8 publicações, fornecido em 200 µg/ml
raised against amino acids 171-470 mapping within an internal region of Dyskerin of human origin
Anti-Dyskerin Anticorpo (H-3) é recomendado para a detecção de Dyskerin de mouse, rat e human origem em WB, IP, IF e ELISA
Anti-Dyskerin Antibody (H-3) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
dispnonível como reagente TransCruz para o uso em ChIP (sc-373956 X, 200 µg/0.1 ml)
Entre em contato conosco e receba GRATUITAMENTE um amostra de 10 µg de Dyskerin (H-3): sc-373956.
m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP) is the preferred detection reagent for Dyskerin Antibody (H-3) for WB applications. This reagent is now offered in a bundle with Dyskerin Antibody (H-3) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
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Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
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Dyskerin Antibody (H-3) is a high quality monoclonal Dyskerin antibody (also designated DKC1 antibody) suitable for the detection of the Dyskerin protein of mouse, rat and human origin. Dyskerin Antibody (H-3) is available as both the non-conjugated anti-Dyskerin antibody form, as well as multiple conjugated forms of anti-Dyskerin antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Dyskerin (NAP57) associates with the chaperone protein Nopp140 and forms a small ribonucleoprotein particle with GAR1 (NOLA1), NHP2 (NOLA2) and Nop10 for the isomerization of uridine to pseudouridine. GAR1, NHP2 and dyskerin localize to the dense fibrillar component of the nucleolus and in nuclear Cajal bodies. The dyskerin gene maps to chromosome Xq28. Missense mutations in the dyskerin gene interfere with normal nuclear localization of dyskerin and cause Dyskeratosis congenita (DKC). DKC is a rare, X-linked bone marrow disorder characterized by cutaneous hyperpigmentation, dystrophy of the nails, atrophy of the testicles and leukoplakia of the oral mucosa. The GAR1 gene maps to chromosome 4q25. The NHP2 gene maps to chromosome 5q35.3 and encodes a 155-amino acid protein (2,7).
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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