CD45 Anticorpo (T29/33): sc-18901
- CD45 Anticorpo T29/33é um anticorpo monoclonal produzido em camundongo IgG1 κ, citado em 6 publicações, fornecido em 200 µg/ml
- com anticorpos contra a linha celular human, CCRF-CEM
- recomendado para a detecção de CD45 of human origin by WB, IP, IF, IHC(P) and FCM
- disponível conjugado tanto à ficoeritrina como à FITC para IF, IHC(P) e FCM
- See CD45 (35-Z6): sc-1178 for additional antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP e m-IgGκ BP-HRP são os reagentes de deteção secundários preferidos para CD45 Anticorpo (T29/33) para aplicações WB and IHC(P). Estes reagentes são agora oferecidos em conjuntos com CD45 Anticorpo (T29/33) (ver informações para encomenda abaixo).
CD45 has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45 are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5 and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45, while the intracellular domain is conserved. CD45 functions as a phosphotyrosine phosphatase, a vital component for efficient tyrosine phosphorylation induction by the TCR/CD3 complex. The tyrosine phosphatase activity of CD45 is contained within the conserved intracellular domain. Src and Syk family protein tyrosine kinases are utilized by the TCR/CD3 complex to initiate signaling cascades. Several members of these two families, including Lck, Fyn and ZAP-70, have been implicated as physiological substrates of CD45.
Informacoes sobre ordens
| Nome do Produto | Numero de Catalogo | UNID | Preco | Qde | FAVORITOS | |
CD45 Anticorpo (T29/33) | sc-18901 | 200 µg/ml | $316.00 | |||
Pacote do CD45 (T29/33): m-IgG Fc BP-HRP | sc-536611 | 200 µg Ab; 10 µg BP | $354.00 | |||
Pacote do CD45 (T29/33): m-IgGκ BP-HRP | sc-533767 | 200 µg Ab; 40 µg BP | $354.00 | |||
Pacote do CD45 (T29/33): m-IgG1 BP-HRP | sc-544706 | 200 µg Ab; 20 µg BP | $354.00 | |||
CD45 Anticorpo (T29/33) FITC | sc-18901 FITC | 200 µg/ml | $330.00 | |||
CD45 Anticorpo (T29/33) PE | sc-18901 PE | 200 µg/ml | $343.00 |