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α-1-Microglobulin Antibody (10A12) is an IgG1 mouse monoclonal alpha-1-Microglobulin antibody (also designated α-1-Microglobulin antibody) that detects the alpha-1-Microglobulin protein of human origin by WB, IP and ELISA. α-1-Microglobulin Antibody (10A12) is available as the non-conjugated anti-alpha-1-Microglobulin antibody. AMBP (alpha-1-microglobulin/bikunin precursor) is a 352 amino acid protein that is proteolytically cleaved to produce three active peptides, designated α-1-Microglobulin, Bikunin and ITI-LC (inter-α-trypsin light chain). α-1-Microglobulin, also known as protein HC, is a 184 amino acid secreted peptide that exists as a monomer and is present in many physiological fluids, including urine, plasma and cerebrospinal fluid. Interacting with Fibronectin, α-1-Microglobulin belongs to the lipocalin family of transport proteins and may participate in the regulation of inflammatory processes, as well as in the autocatalytic creation of chromophores. The gene encoding the AMBP precursor maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster.
Alexa Fluor® é uma marca comercial da Molecular Probes Inc., OR., EUA
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Informacoes sobre ordens
Nome do Produto | Numero de Catalogo | UNID | Preco | Qde | FAVORITOS | |
α-1-Microglobulin Anticorpo (10A12) | sc-135665 | 100 µl | $316.00 |