Date published: 2025-9-14

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α-1-Microglobulin Anticorpo (10A12): sc-135665

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Fichas de dados
  • alpha-1-Microglobulin Anticorpo 10A12é um anticorpo monoclonal produzido em camundongo IgG1 α-1-Microglobulin anticorpo, citado em 2 publicações, fornecido em 100 µl
  • ativado contra Bikunin purificado a partir de plasma de origem human
  • recomendado para a detecção de AMBP and α-1-Microglobulin of human origin by WB, IP and ELISA
  • Atualmente, ainda não concluímos a identificação do(s) reagente(s) de deteção secundário(s) preferido(s) para α-1-Microglobulin Anticorpo (10A12). Este trabalho está em curso.

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α-1-Microglobulin Antibody (10A12) is an IgG1 mouse monoclonal alpha-1-Microglobulin antibody (also designated α-1-Microglobulin antibody) that detects the alpha-1-Microglobulin protein of human origin by WB, IP and ELISA. α-1-Microglobulin Antibody (10A12) is available as the non-conjugated anti-alpha-1-Microglobulin antibody. AMBP (alpha-1-microglobulin/bikunin precursor) is a 352 amino acid protein that is proteolytically cleaved to produce three active peptides, designated α-1-Microglobulin, Bikunin and ITI-LC (inter-α-trypsin light chain). α-1-Microglobulin, also known as protein HC, is a 184 amino acid secreted peptide that exists as a monomer and is present in many physiological fluids, including urine, plasma and cerebrospinal fluid. Interacting with Fibronectin, α-1-Microglobulin belongs to the lipocalin family of transport proteins and may participate in the regulation of inflammatory processes, as well as in the autocatalytic creation of chromophores. The gene encoding the AMBP precursor maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster.

Para uso em exclusivo em pesquisa. Não se destina a uso em diagnostico e tratamento.

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Referencias do α-1-Microglobulin Anticorpo (10A12):

  1. O processamento da lipocalina alfa(1)-microglobulina pela hemoglobina induz propriedades de ligação ao heme e de degradação do heme.  |  Allhorn, M., et al. 2002. Blood. 99: 1894-901. PMID: 11877257
  2. A alfa-1-microglobulina humana está ligada covalentemente a cromóforos derivados da quinurenina.  |  Sala, A., et al. 2004. J Biol Chem. 279: 51033-41. PMID: 15452109
  3. Estrutura do gene humano alfa 1-microglobulina-bikunin.  |  Vetr, H. and Gebhard, W. 1990. Biol Chem Hoppe Seyler. 371: 1185-96. PMID: 1708673
  4. Regulação positiva da alfa1-microglobulina pela hemoglobina e espécies reactivas de oxigénio em linhas de hepatoma e células sanguíneas.  |  Olsson, MG., et al. 2007. Free Radic Biol Med. 42: 842-51. PMID: 17320766
  5. Estudos SAXS da proteína humana HC (alfa1-microglobulina).  |  Kozak, M. and Grubb, A. 2007. Protein Pept Lett. 14: 425-9. PMID: 17584166
  6. A lipocalina alfa1-microglobulina tem atividade de eliminação de radicais.  |  Akerström, B., et al. 2007. J Biol Chem. 282: 31493-503. PMID: 17766242
  7. Sequência de um cDNA de comprimento total que codifica a proteína humana HC (alfa 1 microglobulina).  |  Traboni, C. and Cortese, R. 1986. Nucleic Acids Res. 14: 6340. PMID: 2428011

Informacoes sobre ordens

Nome do ProdutoNumero de CatalogoUNIDPrecoQdeFAVORITOS

α-1-Microglobulin Anticorpo (10A12)

sc-135665
100 µl
$316.00

What is the concentration of sc-135665: α-1-Microglobulin (10A12) monoclonal antibody?

Asked by: jerojero
Thank you for your question. The concentration of α-1-Microglobulin (10A12): sc-135665 has not been characterized. We provide 100 µl of this antibody
Answered by: Technical Support
Date published: 2023-09-20
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Rated 5 out of 5 by from Good for Western BlotAntibody works for Western blot with conditioned media from primary human hepatocytes in published research -SCBT QC
Date published: 2023-09-14
Rated 5 out of 5 by from WB publishable data with human bloodWB publishable data with human blood - SCBT Publication Review
Date published: 2014-01-03
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α-1-Microglobulin Anticorpo (10A12) is rated 5.0 out of 5 by 2.
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