ABHD14B Activators refers to a class of chemical compounds specifically identified or designed to enhance the expression or activity of the ABHD14B enzyme, a member of the metabolic serine hydrolase family. These activators are characterized by their unique interaction with the ABHD14B enzyme, influencing its biochemical pathway. The primary function of these activators is to increase the catalytic efficiency or expression levels of ABHD14B. This is achieved through various molecular mechanisms, including altering the enzyme's conformation for optimal activity, facilitating the binding of substrates, or modulating the gene expression to increase the production of ABHD14B. The chemical nature of these activators can be diverse, ranging from small organic molecules to larger complex structures. Each activator is designed to interact specifically with the ABHD14B enzyme, often targeting unique sites on the enzyme to prevent off-target effects.
The development and study of ABHD14B Activators are rooted in a deep understanding of the enzyme's structure and function. ABHD14B, being a part of the broader serine hydrolase family, plays a role in diverse hydrolytic reactions involving compounds like lipids, esters, and amides. The activators are thus tailored to engage with this enzyme in a manner that maximizes its intrinsic activity. This engagement might involve stabilizing the active site conformation, protecting the enzyme from deactivation, or enhancing the enzyme's affinity for its natural substrates. The intricate design of these activators is based on detailed biochemical and biophysical studies, including enzyme kinetics, crystallography, and computational modeling. Through these studies, specific molecular interactions between the activators and ABHD14B are elucidated, guiding the refinement of these compounds for optimal interaction with the enzyme. The study of ABHD14B Activators, therefore, represents a sophisticated area of biochemistry and molecular biology, focusing on the precise modulation of a specific enzymatic function.
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| Nome do Produto | CAS # | Numero de Catalogo | Quantidade | Preco | Uso e aplicacao | NOTAS |
|---|---|---|---|---|---|---|
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
Um inibidor da DNA metiltransferase, que leva à desmetilação do DNA, afectando potencialmente a expressão genética, incluindo genes que codificam proteínas de dedo de zinco como o ZNF544. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Um inibidor da HDAC que altera a estrutura da cromatina e a expressão genética, influenciando potencialmente a atividade transcricional do ZNF544. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
Sendo também um inibidor da HDAC, pode ter impacto na remodelação da cromatina e na expressão genética, afectando potencialmente as actividades de regulação da transcrição do ZNF544. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Influencia a expressão genética através dos receptores de ácido retinóico, afectando potencialmente os factores de transcrição, incluindo o ZNF544. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $70.00 $160.00 $290.00 | 2 | |
Modula a expressão genética através do recetor da vitamina D, influenciando potencialmente a expressão ou a função de factores de transcrição como o ZNF544. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Influencia várias vias de sinalização celular, afectando potencialmente os factores de transcrição e as proteínas envolvidas na regulação dos genes, incluindo o ZNF544. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
Um polifenol que pode afetar a expressão genética e as vias de stress celular, influenciando potencialmente proteínas como ZNF544 envolvidas na regulação da transcrição. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Tem impacto na atividade da sirtuína e na expressão genética, modulando potencialmente os factores de transcrição, incluindo o ZNF544. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
Influencia a expressão genética e as vias de desintoxicação celular, afectando potencialmente factores de transcrição como o ZNF544. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Um inibidor da tirosina quinase que pode modular as vias de sinalização e a expressão genética, afectando potencialmente o papel do ZNF544 na regulação da transcrição. | ||||||