The term RAET1L refers to a gene or protein that may be related to the RAET1 (Retinoic Acid Early Transcript 1) family, which is a group of proteins that can be involved in cellular signaling processes. RAET1L Activators would include molecules designed to modulate the function of the RAET1L protein. These activators would be engineered to increase the functional activity of RAET1L, either by enhancing its expression, promoting its stability, facilitating its interaction with other signaling molecules, or by directly stimulating its activity in signal transduction pathways. The discovery of such activators would typically involve a deep understanding of the biological role of RAET1L, the pathways it participates in, and the structural features that are key to its function.
To identify RAET1L Activators, researchers would first develop an assay system to measure the activity of RAET1L. These assays could be based on the detection of downstream signaling events triggered by RAET1L activation, changes in gene expression profiles, or direct measurement of biochemical activity if the RAET1L protein has enzymatic functions. With an effective assay in place, large libraries of small molecules could be screened to identify compounds that enhance RAET1L activity. Such screening campaigns would yield initial 'hit' molecules that, after being identified, would require further validation to confirm their specificity and direct effect on RAET1L. These secondary assays might include various controls with related proteins to ensure the specificity of the activator for RAET1L, as well as dose-response and kinetic studies to characterize the interaction dynamics. Subsequent research would likely delve into the molecular mechanism by which these activators enhance RAET1L function. Approaches such as mutational analysis of the RAET1L protein, or biophysical methods like nuclear magnetic resonance (NMR) spectroscopy, could provide insights into how the activators bind and stimulate RAET1L. Understanding the interaction between RAET1L and its activators could provide valuable information about the protein's role in cellular processes.
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| Nome do Produto | CAS # | Numero de Catalogo | Quantidade | Preco | Uso e aplicacao | NOTAS |
|---|---|---|---|---|---|---|
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
Como inibidor da DNA metiltransferase, pode desmetilar os promotores de genes e aumentar a expressão de genes como o RAET1L. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
Ao inibir as histonas desacetilases, o butirato de sódio pode afetar a estrutura da cromatina e a expressão dos genes, incluindo potencialmente o RAET1L. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Conhecido por regular a expressão de genes, o ácido retinóico pode também influenciar a expressão de RAET1L, dada a semelhança de nomenclatura. | ||||||
Rosiglitazone | 122320-73-4 | sc-202795 sc-202795A sc-202795C sc-202795D sc-202795B | 25 mg 100 mg 500 mg 1 g 5 g | $118.00 $320.00 $622.00 $928.00 $1234.00 | 38 | |
Um agonista PPAR-gama que pode modular a inflamação, afectando potencialmente a expressão de proteínas relacionadas com o sistema imunitário, como a RAET1L. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Com propriedades anti-inflamatórias e antioxidantes, a curcumina pode modular a expressão de genes relacionados com o sistema imunitário, incluindo o RAET1L. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Este composto tem vários efeitos biológicos, incluindo a modulação da função imunitária, o que pode potencialmente influenciar a expressão de RAET1L. | ||||||
Arsenic(III) oxide | 1327-53-3 | sc-210837 sc-210837A | 250 g 1 kg | $87.00 $224.00 | ||
Utilizado no tratamento de certas leucemias, o trióxido de arsénio pode induzir respostas de stress nas células, afectando possivelmente a expressão de RAET1L. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
A EGCG, a principal catequina do chá verde, demonstrou modular as respostas imunitárias e pode afetar a expressão de RAET1L. | ||||||