Date published: 2025-10-29

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RAET1L Ativadores

The term RAET1L refers to a gene or protein that may be related to the RAET1 (Retinoic Acid Early Transcript 1) family, which is a group of proteins that can be involved in cellular signaling processes. RAET1L Activators would include molecules designed to modulate the function of the RAET1L protein. These activators would be engineered to increase the functional activity of RAET1L, either by enhancing its expression, promoting its stability, facilitating its interaction with other signaling molecules, or by directly stimulating its activity in signal transduction pathways. The discovery of such activators would typically involve a deep understanding of the biological role of RAET1L, the pathways it participates in, and the structural features that are key to its function.

To identify RAET1L Activators, researchers would first develop an assay system to measure the activity of RAET1L. These assays could be based on the detection of downstream signaling events triggered by RAET1L activation, changes in gene expression profiles, or direct measurement of biochemical activity if the RAET1L protein has enzymatic functions. With an effective assay in place, large libraries of small molecules could be screened to identify compounds that enhance RAET1L activity. Such screening campaigns would yield initial 'hit' molecules that, after being identified, would require further validation to confirm their specificity and direct effect on RAET1L. These secondary assays might include various controls with related proteins to ensure the specificity of the activator for RAET1L, as well as dose-response and kinetic studies to characterize the interaction dynamics. Subsequent research would likely delve into the molecular mechanism by which these activators enhance RAET1L function. Approaches such as mutational analysis of the RAET1L protein, or biophysical methods like nuclear magnetic resonance (NMR) spectroscopy, could provide insights into how the activators bind and stimulate RAET1L. Understanding the interaction between RAET1L and its activators could provide valuable information about the protein's role in cellular processes.

VEJA TAMBÉM

Nome do ProdutoCAS #Numero de CatalogoQuantidadePrecoUso e aplicacaoNOTAS

5-Aza-2′-Deoxycytidine

2353-33-5sc-202424
sc-202424A
sc-202424B
25 mg
100 mg
250 mg
$214.00
$316.00
$418.00
7
(1)

Como inibidor da DNA metiltransferase, pode desmetilar os promotores de genes e aumentar a expressão de genes como o RAET1L.

Sodium Butyrate

156-54-7sc-202341
sc-202341B
sc-202341A
sc-202341C
250 mg
5 g
25 g
500 g
$30.00
$46.00
$82.00
$218.00
19
(3)

Ao inibir as histonas desacetilases, o butirato de sódio pode afetar a estrutura da cromatina e a expressão dos genes, incluindo potencialmente o RAET1L.

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$65.00
$319.00
$575.00
$998.00
28
(1)

Conhecido por regular a expressão de genes, o ácido retinóico pode também influenciar a expressão de RAET1L, dada a semelhança de nomenclatura.

Rosiglitazone

122320-73-4sc-202795
sc-202795A
sc-202795C
sc-202795D
sc-202795B
25 mg
100 mg
500 mg
1 g
5 g
$118.00
$320.00
$622.00
$928.00
$1234.00
38
(1)

Um agonista PPAR-gama que pode modular a inflamação, afectando potencialmente a expressão de proteínas relacionadas com o sistema imunitário, como a RAET1L.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$36.00
$68.00
$107.00
$214.00
$234.00
$862.00
$1968.00
47
(1)

Com propriedades anti-inflamatórias e antioxidantes, a curcumina pode modular a expressão de genes relacionados com o sistema imunitário, incluindo o RAET1L.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$60.00
$185.00
$365.00
64
(2)

Este composto tem vários efeitos biológicos, incluindo a modulação da função imunitária, o que pode potencialmente influenciar a expressão de RAET1L.

Arsenic(III) oxide

1327-53-3sc-210837
sc-210837A
250 g
1 kg
$87.00
$224.00
(0)

Utilizado no tratamento de certas leucemias, o trióxido de arsénio pode induzir respostas de stress nas células, afectando possivelmente a expressão de RAET1L.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$42.00
$72.00
$124.00
$238.00
$520.00
$1234.00
11
(1)

A EGCG, a principal catequina do chá verde, demonstrou modular as respostas imunitárias e pode afetar a expressão de RAET1L.