Date published: 2025-10-30

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Gamma-glutamyltransferase (GGT) Ativadores

Gamma-glutamyltransferase (GGT) is an enzyme that plays a crucial role in cellular redox regulation and the metabolism of glutathione, a vital antioxidant molecule. GGT signaling encompasses a network of interactions and pathways involved in maintaining cellular redox balance and managing glutathione levels. This enzyme is primarily localized on the cell membrane and functions to cleave gamma-glutamyl bonds in various substrates, including glutathione. GGT signaling is closely tied to the control of glutathione homeostasis within cells. By catalyzing the breakdown of extracellular glutathione and other gamma-glutamyl compounds, GGT helps regulate the levels of these molecules, which in turn influence redox signaling and antioxidant defense mechanisms.

Gamma-glutamyltransferase (GGT) Activators comprises compounds that have the ability to enhance GGT activity. These activators can interact directly or indirectly with GGT, leading to an increase in its catalytic efficiency. Indirect activators may influence cellular processes that impact GGT expression or activation. The study of GGT activators is essential for unraveling the intricate mechanisms of redox regulation and cellular antioxidant defenses. By understanding how these compounds influence GGT signaling, researchers gain insights into the broader context of cellular redox balance and antioxidant responses, shedding light on fundamental cellular processes that are vital for maintaining health and homeostasis.

Nome do ProdutoCAS #Numero de CatalogoQuantidadePrecoUso e aplicacaoNOTAS

Glutathione, reduced

70-18-8sc-29094
sc-29094A
10 g
1 kg
$76.00
$2050.00
8
(2)

O próprio glutatião pode servir como ativador da GGT. A GGT desempenha um papel na manutenção dos níveis de glutatião celular, clivando as ligações gama-glutamilo no glutatião extracelular, o que pode ativar indiretamente a GGT.

Iron

7439-89-6sc-215190
sc-215190A
500 g
2 kg
$68.00
$176.00
(0)

Foi demonstrado que os iões de ferro, particularmente os iões ferrosos (Fe2+), activam a GGT. O ferro pode ligar-se à GGT e modular a sua atividade, aumentando potencialmente a sua eficiência catalítica.

S-Nitrosoglutathione (GSNO)

57564-91-7sc-200349
sc-200349B
sc-200349A
sc-200349C
10 mg
25 mg
50 mg
100 mg
$85.00
$206.00
$339.00
$449.00
15
(1)

O GSNO é um dador de óxido nítrico que pode ativar a GGT. Pode estimular indiretamente a atividade da GGT ao afetar o estado redox da célula e o metabolismo do glutatião.

L-Cysteine

52-90-4sc-286072
sc-286072A
sc-286072B
sc-286072C
sc-286072D
25 g
100 g
500 g
5 kg
10 kg
$50.00
$110.00
$440.00
$1128.00
$2135.00
1
(1)

A L-cisteína pode ativar a GGT fornecendo grupos tiol que interagem com o local ativo da enzima.

Insulin Anticorpo ()

11061-68-0sc-29062
sc-29062A
sc-29062B
100 mg
1 g
10 g
$153.00
$1224.00
$12239.00
82
(1)

A insulina é uma hormona que regula o metabolismo da glucose. Pode ativar a GGT, possivelmente afectando o estado redox da célula ou modulando a expressão da GGT.