β-defensin 121 is a protein that belongs to the β-defensin family, we can infer general characteristics based on the known properties of β-defensins. These are small, cysteine-rich cationic peptides that are an integral part of the innate immune defense, mainly due to their antimicrobial activity against a broad spectrum of pathogens, including bacteria, viruses, and fungi. Their mechanism of action typically involves permeabilization of microbial membranes, leading to cell death.The β-defensins are also known for their ability to modulate the immune response by acting as signaling molecules. They can attract various immune cells, such as macrophages and dendritic cells, to the site of infection, thereby enhancing the adaptive immune response. Moreover, they may influence the production of cytokines and chemokines, thus playing a role in inflammatory responses.
These peptides are predominantly expressed in epithelial cells, which form barriers on the skin, as well as in the respiratory, gastrointestinal, and urogenital tracts. This strategic expression allows them to act at the front lines of defense against microbial invasion. Expression of β-defensins can be upregulated in response to microbial challenge or inflammatory signals, providing a dynamic response to infection.Should a "β-defensin 121" exist, it would likely share these structural and functional characteristics, contributing to the host's defense mechanisms by both direct antimicrobial action and immune system modulation.
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| Nome do Produto | CAS # | Numero de Catalogo | Quantidade | Preco | Uso e aplicacao | NOTAS |
|---|---|---|---|---|---|---|
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $70.00 $160.00 $290.00 | 2 | |
A vitamina D3 pode aumentar a expressão de péptidos antimicrobianos, incluindo β-defensinas, através da via do recetor da vitamina D (VDR). | ||||||
Butyric acid | 107-92-6 | sc-214640 sc-214640A | 1 kg 10 kg | $63.00 $174.00 | ||
O butirato, um ácido gordo de cadeia curta produzido pelo microbiota intestinal, pode aumentar a expressão da defensina no epitélio intestinal. | ||||||
1α,25-Dihydroxyvitamin D3 | 32222-06-3 | sc-202877B sc-202877A sc-202877C sc-202877D sc-202877 | 50 µg 1 mg 5 mg 10 mg 100 µg | $325.00 $632.00 $1428.00 $2450.00 $400.00 | 32 | |
A forma ativa da vitamina D, desempenha um papel na estimulação do sistema imunitário e pode aumentar a expressão da β-defensina. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
O ácido retinóico, derivado da vitamina A, influencia as respostas imunitárias e pode aumentar a expressão da β-defensina. | ||||||
Lipopolysaccharide, E. coli O55:B5 | 93572-42-0 | sc-221855 sc-221855A sc-221855B sc-221855C | 10 mg 25 mg 100 mg 500 mg | $96.00 $166.00 $459.00 $1615.00 | 12 | |
O LPS, um componente da membrana externa das bactérias Gram-negativas, pode induzir a expressão da β-defensina como parte da resposta imunitária. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $47.00 | ||
O zinco é crucial para a função imunitária e foi demonstrado que influencia a expressão de várias defensinas. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
O resveratrol, um polifenol, pode modular as respostas imunitárias e potencialmente aumentar a expressão da β-defensina. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
A curcumina tem propriedades anti-inflamatórias e pode influenciar a expressão de péptidos antimicrobianos, incluindo as β-defensinas. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
A EGCG, presente no chá verde, possui propriedades anti-inflamatórias e pode afetar a expressão da β-defensina. | ||||||
Lactoferrin | 146897-68-9 | sc-394420 sc-394420A sc-394420B sc-394420C | 10 mg 50 mg 100 mg 1 g | $120.00 $400.00 $569.00 $1465.00 | ||
A lactoferrina, um componente do sistema imunitário inato, pode modular as respostas imunitárias e potencialmente a expressão da β-defensina. | ||||||