Molecular structure of Ampicillin, CAS Number: 69-53-4
Ampicillin (CAS 69-53-4)
See product citations (11)
Alternate Names:
Ampicillin is also known as 6-[D(−)-a-Aminophenylacetamido]penicillanic acid. Note: This is the free acid form.
Application:
Ampicillin is a semi-synthetic antibiotic structurally related to penicillin, and able to inhibit bacterial cell wall biogenesis.
CAS Number:
69-53-4
Purity:
≥96%
Molecular Weight:
349.40
Molecular Formula:
C16H19N3O4S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Ampicillin is an antibiotic that is structurally related to penicillin. It belongs to the family of the α-aminobenzyl penicillin group, which differs from penicillin by an amino group that facilitates membrane penetration. A unique feature of Ampicillin is its ability to inhibit bacterial cell wall biogenesis. The action of Ampicillin is the interference directly of peptidoglycan biosynthesis, leading to structural instability and death of bacteria. In addition to its role as a broad-class antibiotic, it can be used as a selective agent in several types of isolation media.
Ampicillin (CAS 69-53-4) References
- Comparative effects of amoxycillin and ampicillin in the treatment of experimental mouse infections. | Comber, KR., et al. 1975. Antimicrob Agents Chemother. 7: 179-85. PMID: 1094950
- Antibiotic susceptibility of invasive Haemophilus influenzae strains in Canada. | Sill, ML. and Tsang, RS. 2008. Antimicrob Agents Chemother. 52: 1551-2. PMID: 18227189
- Ampicillin-loaded liposomes and nanoparticles: comparison of drug loading, drug release and in vitro antimicrobial activity. | Fattal, E., et al. 1991. J Microencapsul. 8: 29-36. PMID: 1880689
- Experimental determination of ampicillin adsorption to nanometer-size Al2O3 in water. | Peterson, JW., et al. 2010. Chemosphere. 80: 1268-73. PMID: 20638098
- Ampicillin-ester bonded branched polymers: characterization, cyto-, genotoxicity and controlled drug-release behaviour. | Oledzka, E., et al. 2014. Molecules. 19: 7543-56. PMID: 24914899
- In vitro evaluation of ampicillin-gentamicin interactions. | Van der Bijl, P. and Seifart, HI. 1989. J Oral Maxillofac Surg. 47: 489-94. PMID: 2709220
- Adsorption and release of ampicillin antibiotic from ordered mesoporous silica. | Nairi, V., et al. 2017. J Colloid Interface Sci. 497: 217-225. PMID: 28285049
- Sulbactam/ampicillin. A review of its antibacterial activity, pharmacokinetic properties, and therapeutic use. | Campoli-Richards, DM. and Brogden, RN. 1987. Drugs. 33: 577-609. PMID: 3038500
- Efficiency of Ampicillin-Associated Biogenic Ferrihydrite Nanoparticles in Combination with a Magnetic Field for Local Treatment of Burns. | Inzhevatkin, EV., et al. 2020. Bull Exp Biol Med. 169: 683-686. PMID: 32990856
- Influence of ampicillin elimination half-life on in-vitro bactericidal effect. | White, CA. and Toothaker, RD. 1985. J Antimicrob Chemother. 15 Suppl A: 257-60. PMID: 3980329
- Studies on the absorption of pivampicillin and ampicillin. | Hultberg, ER. and Backelin, B. 1972. Scand J Infect Dis. 4: 149-53. PMID: 4560876
- Ampicillin systemic bioavailability: the influence of dosage form. | Dugal, R., et al. 1974. J Clin Pharmacol. 14: 513-9. PMID: 4610014
- Amoxycillin, talampicillin, and ampicillin. | Leigh, DA. 1976. Br Med J. 2: 232. PMID: 974505
- Ampicillin | Eugene Ivashkiv. 1973. Analytical Profiles of Drug Substances. 2: 1-61.
Inhibitor of:
Bordetella pertussis, Brucella abortus, Diphtheria Toxin, E. coli, Edwardsiella tarda, Enrofloxacin, Erwinia herbicola, Salmonella (Enterobacterales), Salmonella paratyphi 0-2, Salmonella typhimurium 0-4, Shigella dysenteriae, Streptococcus agalactiae, and Streptococcus Group B.Activator of:
Ampicillin, DDT, Dynactin 2, Grim19, M13 filamentous phage, PBP, PHOSPHO2, REEP5, and Vancomycin.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ampicillin, 100 mg | sc-210812 | 100 mg | $30.00 | |||
Ampicillin, 1 g | sc-210812A | 1 g | $99.00 | |||
Ampicillin, 5 g | sc-210812B | 5 g | $150.00 | |||
Ampicillin, 25 g | sc-210812C | 25 g | $215.00 | |||
Ampicillin, 100 g | sc-210812D | 100 g | $400.00 |