Date published: 2025-10-18

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ZnAF-2F DA (CAS 443302-10-1)

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CAS Number:
443302-10-1
Molecular Weight:
692.66
Molecular Formula:
C38H30F2N4O7
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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A cell-permeable diacetyl derivative hydrolyzed by esterase in the cytosol to yield the metabolite ZnAF-2F, which is retained within the cell.


ZnAF-2F DA (CAS 443302-10-1) References

  1. Improvement and biological applications of fluorescent probes for zinc, ZnAFs.  |  Hirano, T., et al. 2002. J Am Chem Soc. 124: 6555-62. PMID: 12047174
  2. Mossy fiber Zn2+ spillover modulates heterosynaptic N-methyl-D-aspartate receptor activity in hippocampal CA3 circuits.  |  Ueno, S., et al. 2002. J Cell Biol. 158: 215-20. PMID: 12119362
  3. Synthetic fluorescent sensors for studying the cell biology of metals.  |  Domaille, DW., et al. 2008. Nat Chem Biol. 4: 168-75. PMID: 18277978
  4. Photoluminescence imaging of Zn(2+) in living systems.  |  Chen, Y., et al. 2015. Chem Soc Rev. 44: 4517-46. PMID: 25747236
  5. Development of Functional Fluorescent Molecular Probes for the Detection of Biological Substances.  |  Suzuki, Y. and Yokoyama, K. 2015. Biosensors (Basel). 5: 337-63. PMID: 26095660
  6. Fluorescent detection of zinc in biological systems: recent development on the design of chemosensors and biosensors  |  Jiang, P., & Guo, Z. 2004. Coordination chemistry reviews. 248(1-2): 205-229.
  7. Zinc metalloneurochemistry: physiology, pathology, and probes  |  Chang, C. J., & Lippard, S. J. 2006. Neurodegenerative Diseases and Metal Ions. 1: 321-370.
  8. Zn induces changes in activities of mitochondrial respiratory chain complexes and emissions of floral volatiles in  |  Zhu, W., Dai, J., & Wang, J. 2022. Folia Horticulturae. 34(1): 105-124.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

ZnAF-2F DA, 1 mg

sc-296862
1 mg
$700.00