Ziprasidone-d8 (CAS 1126745-58-1)

Ziprasidone-d8 is a stable isotope-labeled analogue of ziprasidone, where eight hydrogen atoms are replaced with deuterium. This compound is utilized in research as an internal standard for the quantification of ziprasidone using mass spectrometric techniques, such as liquid chromatography-tandem mass spectrometry (LC-MS/MS). The incorporation of deuterium atoms into the molecule provides a mass difference that allows for the clear distinction between ziprasidone-d8 and the non-labeled ziprasidone in analytical assays. Researchers utilize ziprasidone-d8 to investigate the absorption, distribution, metabolism, and excretion (ADME) of ziprasidone in various biological matrices. The application of this deuterated compound is particularly valuable in the field of analytical chemistry to calibrate instruments and validate methodologies that require precise and accurate measurements of ziprasidone in experimental and biological samples. The use of ziprasidone-d8 aids in enhancing the reliability of research findings in studies where understanding the behavior of ziprasidone is critical.