Date published: 2026-5-7

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Zelkovamycin (CAS 221197-33-7)

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Application:
Zelkovamycin is a cyclic peptide antibiotic
CAS Number:
221197-33-7
Molecular Weight:
779.86
Molecular Formula:
C36H45N9O9S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Zelkovamycin is a cyclic peptide antibiotic. Inhibits protein synthesis in Gram-positive bacteria. The compound′s unique properties also lend itself to potential uses in the field of biotechnology, where it might contribute to the development of novel bio-based products or processes. Its activity at the molecular level can provide insights into the design of new materials or the improvement of existing ones, emphasizing the importance of such compounds in advancing scientific knowledge and technological innovation.


Zelkovamycin (CAS 221197-33-7) References

  1. Zelkovamycin, a new cyclic peptide antibiotic from Streptomyces sp. K96-0670. I. Production, isolation and biological properties.  |  Zhang, H., et al. 1999. J Antibiot (Tokyo). 52: 29-33. PMID: 10092194
  2. Zelkovamycin, a new cyclic peptide antibiotic from Streptomyces sp. K96-0670. II. Structure elucidation.  |  Tabata, N., et al. 1999. J Antibiot (Tokyo). 52: 34-9. PMID: 10092195
  3. Argyrins, immunosuppressive cyclic peptides from myxobacteria. II. Structure elucidation and stereochemistry.  |  Vollbrecht, L., et al. 2002. J Antibiot (Tokyo). 55: 715-21. PMID: 12374385
  4. Microbiaeratin, a new natural indole alkaloid from a Microbispora aerata strain, isolated from Livingston Island, Antarctica.  |  Ivanova, V., et al. 2007. Prep Biochem Biotechnol. 37: 161-8. PMID: 17454826
  5. The role of aromatic L-amino acid decarboxylase in bacillamide C biosynthesis by Bacillus atrophaeus C89.  |  Yuwen, L., et al. 2013. Sci Rep. 3: 1753. PMID: 23628927
  6. Efficacies of quorum sensing inhibitors, piericidin A and glucopiericidin A, produced by Streptomyces xanthocidicus KPP01532 for the control of potato soft rot caused by Erwinia carotovora subsp. atroseptica.  |  Kang, JE., et al. 2016. Microbiol Res. 184: 32-41. PMID: 26856451
  7. Solvent-free synthesis of bacillamide analogues as novel cytotoxic and anti-inflammatory agents.  |  Kumar, S., et al. 2016. Eur J Med Chem. 123: 718-726. PMID: 27521588
  8. Zelkovamycin is an OXPHOS Inhibitory Member of the Argyrin Natural Product Family.  |  Krahn, D., et al. 2020. Chemistry. 26: 8524-8531. PMID: 32250484
  9. Zelkovamycins B-E, Cyclic Octapeptides Containing Rare Amino Acid Residues from an Endophytic Kitasatospora sp.  |  Hao, X., et al. 2020. Org Lett. 22: 9346-9350. PMID: 33216552
  10. Actinomadura graeca sp. nov.: A novel producer of the macrocyclic antibiotic zelkovamycin.  |  Tarantini, FS., et al. 2021. PLoS One. 16: e0260413. PMID: 34847153
  11. Zelkovamycins F and G, Cyclopeptides with Cα-Methyl-threonine Residues, from an Endophytic Kitasatospora sp.  |  Hao, X., et al. 2022. J Nat Prod. 85: 1715-1722. PMID: 35715218
  12. Bacillamide F, Extracted from Marine Bacillus atrophaeus C89, Preliminary Effects on Leukemia Cell Lines.  |  Zhang, S., et al. 2022. Biology (Basel). 11: PMID: 36552221

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Zelkovamycin, 250 µg

sc-391085
250 µg
$88.00

Zelkovamycin, 1 mg

sc-391085A
1 mg
$251.00