Date published: 2026-4-3

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White Line Inducing Principle [WLIP] (CAS 135096-89-8)

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Application:
White Line Inducing Principle [WLIP] is a lipodepsipeptide with antimicrobial, antibacterial and antifungal properties
CAS Number:
135096-89-8
Molecular Weight:
1126.4
Molecular Formula:
C54H95N9O16
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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The White Line Inducing Principle [WLIP] is for investigating the interplay the behavior of living organisms. This approach encompasses a synthesis method that combines chemical, and genetic techniques to elicit specific behaviors in living organisms. Studies have explored the ramifications of environmental stress on behavior, elucidating the relationship between external factors and organismal responses. Genetic manipulation experiments have also utilized the White Line Inducing Principle [WLIP] to examine how modifications at the genetic level influence behavior. The mechanism of action underlying the White Line Inducing Principle [WLIP] is rooted in the manipulation of processes within the target organism. By intervening in these processes, they are able to induce specific behaviors.


White Line Inducing Principle [WLIP] (CAS 135096-89-8) References

  1. WLIP and tolaasin I, lipodepsipeptides from Pseudomonas reactans and Pseudomonas tolaasii, permeabilise model membranes.  |  Coraiola, M., et al. 2006. Biochim Biophys Acta. 1758: 1713-22. PMID: 16925979
  2. Biological characterization of white line-inducing principle (WLIP) produced by Pseudomonas reactans NCPPB1311.  |  Lo Cantore, P., et al. 2006. Mol Plant Microbe Interact. 19: 1113-20. PMID: 17022175
  3. Bioactive and structural metabolites of pseudomonas and burkholderia species causal agents of cultivated mushrooms diseases.  |  Andolfi, A., et al. 2008. Perspect Medicin Chem. 2: 81-112. PMID: 19787100
  4. The solution structure and self-association properties of the cyclic lipodepsipeptide pseudodesmin A support its pore-forming potential.  |  Sinnaeve, D., et al. 2009. Chemistry. 15: 12653-62. PMID: 19839018
  5. Genetic and functional characterization of cyclic lipopeptide white-line-inducing principle (WLIP) production by rice rhizosphere isolate Pseudomonas putida RW10S2.  |  Rokni-Zadeh, H., et al. 2012. Appl Environ Microbiol. 78: 4826-34. PMID: 22544260
  6. Distinct lipopeptide production systems for WLIP (white line-inducing principle) in Pseudomonas fluorescens and Pseudomonas putida.  |  Rokni-Zadeh, H., et al. 2013. Environ Microbiol Rep. 5: 160-9. PMID: 23757145
  7. WLIP derived from Lasiosphaera fenzlii Reich exhibits anti-tumor activity and induces cell cycle arrest through PPAR-γ associated pathways.  |  Meng, J., et al. 2014. Int Immunopharmacol. 19: 37-44. PMID: 24401848
  8. Complete Genome Sequence of the Sugar Cane Endophyte Pseudomonas aurantiaca PB-St2, a Disease-Suppressive Bacterium with Antifungal Activity toward the Plant Pathogen Colletotrichum falcatum.  |  Mehnaz, S., et al. 2014. Genome Announc. 2: PMID: 24459254
  9. Pseudomonas protegens Pf-5 causes discoloration and pitting of mushroom caps due to the production of antifungal metabolites.  |  Henkels, MD., et al. 2014. Mol Plant Microbe Interact. 27: 733-46. PMID: 24742073
  10. First total synthesis of WLIP: on the importance of correct protecting group choice.  |  De Vleeschouwer, M., et al. 2016. J Pept Sci. 22: 149-55. PMID: 26856688
  11. Secondary Metabolites Production and Plant Growth Promotion by Pseudomonas chlororaphis and P. aurantiaca Strains Isolated from Cactus, Cotton, and Para Grass.  |  Shahid, I., et al. 2017. J Microbiol Biotechnol. 27: 480-491. PMID: 27974729
  12. Biosynthesis and Antimicrobial Activity of Pseudodesmin and Viscosinamide Cyclic Lipopeptides Produced by Pseudomonads Associated with the Cocoyam Rhizosphere.  |  Oni, FE., et al. 2020. Microorganisms. 8: PMID: 32698413
  13. Characterization of the biocontrol activity of three bacterial isolates against the phytopathogen Erwinia amylovora.  |  Dagher, F., et al. 2021. Microbiologyopen. 10: e1202. PMID: 34180603

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

White Line Inducing Principle [WLIP], 1 mg

sc-391074
1 mg
$171.00