Date published: 2026-6-15

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Viridicatin (CAS 129-24-8)

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Alternate Names:
3-Hydroxy-4-phenyl-1H-chinolin-2-one
Application:
Viridicatin is a Penicillium metabolite active against Mycobacterium tuberculosis
CAS Number:
129-24-8
Purity:
≥95%
Molecular Weight:
237.3
Molecular Formula:
C15H11NO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Viridicatin is an alkaloid that has attention in the field of natural product chemistry and mycology. It is found in certain species of the Penicillium genus of fungi and has been the subject of research due to its bioactive properties. In the laboratory, viridicatin is often studied for its potential role in chemical ecology, including the investigation of its function as a defensive agent for fungi against microorganisms. The compound is also of interest for its inhibitory activity against certain enzymes, which could elucidate mechanisms of action for new bioactive molecules. Research involving viridicatin may explore its biosynthetic pathway to understand how such compounds are produced in nature. Additionally, it may be used as a lead compound in the synthesis of new molecules with modified structures in efforts to study structure-activity relationships.


Viridicatin (CAS 129-24-8) References

  1. [The biosynthesis of low-molecular-weight nitrogen-containing secondary metabolite-alkaloids by the resident strains of Penicillium chrysogenum and Penicillium expansum isolated on the board of the Mir space station ].  |  Kozlovskiĭ, AG., et al. 2002. Mikrobiologiia. 71: 773-7. PMID: 12526198
  2. The isolation and some chemical properties of viridicatin, a metabolic product of Penicillium viridicatum Westling.  |  CUNNINGHAM, KG. and FREEMAN, GG. 1952. Biochem J. 52: xxvi. PMID: 13018322
  3. The isolation and some chemical properties of viridicatin, a metabolic product of Penicillium viridicatum Westling.  |  CUNNINGHAM, KG. and FREEMAN, GG. 1953. Biochem J. 53: 328-32. PMID: 13032073
  4. A concise and versatile synthesis of viridicatin alkaloids from cyanoacetanilides.  |  Kobayashi, Y. and Harayama, T. 2009. Org Lett. 11: 1603-6. PMID: 19256518
  5. Characterization of microbial communities and fungal metabolites on field grown strawberries from organic and conventional production.  |  Jensen, B., et al. 2013. Int J Food Microbiol. 160: 313-22. PMID: 23290240
  6. (+)-Cyclopenol, a new naturally occurring 7-membered 2,5-dioxopiperazine alkaloid from the fungus Penicillium sclerotiorum endogenous with the Chinese mangrove Bruguiera gymnorrhiza.  |  Li, J., et al. 2014. J Asian Nat Prod Res. 16: 542-8. PMID: 24773150
  7. Penicillium strains isolated from Slovak grape berries taxonomy assessment by secondary metabolite profile.  |  Santini, A., et al. 2014. Mycotoxin Res. 30: 213-20. PMID: 25109845
  8. Regioselective Ring Expansion of Isatins with In Situ Generated α-Aryldiazomethanes: Direct Access to Viridicatin Alkaloids.  |  Tangella, Y., et al. 2018. Org Lett. 20: 3639-3642. PMID: 29874092
  9. In Vitro Evaluation of the Photoprotective Potential of Quinolinic Alkaloids Isolated from the Antarctic Marine Fungus Penicillium echinulatum for Topical Use.  |  Teixeira, TR., et al. 2021. Mar Biotechnol (NY). 23: 357-372. PMID: 33811268
  10. Synthesis and Mechanistic Insights of the Formation of 3-Hydroxyquinolin-2-ones including Viridicatin from 2-Chloro-N,3-diaryloxirane-2-carboxamides under Acid-Catalyzed Rearrangements.  |  Mamedov, VA., et al. 2021. J Org Chem. 86: 13514-13534. PMID: 34505764
  11. Biosynthesis of Viridicatol in Penicillium palitans Implies a Cytochrome P450-Mediated meta Hydroxylation at a Monoalkylated Benzene Ring.  |  Zhang, ZX., et al. 2022. Org Lett. 24: 262-267. PMID: 34928155
  12. Incorporation of viridicatin alkaloid-like scaffolds into DNA-encoded chemical libraries.  |  Fang, X., et al. 2023. Org Biomol Chem. 21: 2162-2166. PMID: 36799438
  13. 2D-PAGE examination of mRNA populations from Penicillium freii mutants deficient in xanthomegnin biosynthesis.  |  Nicolaisen, M., et al. 1996. Microbiol Res. 151: 285-90. PMID: 8817920
  14. Penicillium discolor, a new species from cheese, nuts and vegetables.  |  Frisvad, JC., et al. 1997. Antonie Van Leeuwenhoek. 72: 119-26. PMID: 9298190
  15. Determination of viridicatin in Penicillium cyclopium by capillary gas chromatography.  |  Bringmann, G., et al. 1997. Anal Biochem. 253: 18-25. PMID: 9356136

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Viridicatin, 1 mg

sc-202385
1 mg
$187.00