Virginiamycin S1 CAS: 23152-29-6
MF: C43H49N7O10
MW: 823.89
A main component of virginiamycin preparations.

Virginiamycin S1 (CAS 23152-29-6)

Virginiamycin S1 | CAS 23152-29-6 is rated 5.0 out of 5 by 1.
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Alternate Names: Staphylomycin S,
Application: Virginiamycin S1 is a main component of virginiamycin preparations
CAS Number: 23152-29-6
Purity: ≥99%
Molecular Weight: 823.89
Molecular Formula: C43H49N7O10
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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Virginiamycin S1 is a streptogramin antibiotic and one of the major active natural product components of Streptomyces virginiae antibiotic secretions. Virginiamycin S1 and virginiamycin M1 work synergistically to produce bacteriocidal action (see Virginiamycin complex, sc-202383), inhibiting protein synthesis of the target in an irreversible fashion upon exposure to both compounds.


References

1. Crooy, P., et al. 1972. J. Antibiot. 25: 371-372. PMID: 4568014
2. Ogata, K., et al. 1978. J. Antibiot. 31: 1313-1315. PMID: 162634
3. Parfait, R., et al. 1980. Proc. Natl. Acad. Sci. U.S.A. 77: 5492-5496. PMID: 6776538
4. Reed, J.W., et al. 1986. J. Nat. Prod. 49: 626-630. PMID: 3097264
5. Prikrylová, V., et al. 1992. Folia Microbiol. 37: 386-388. PMID: 1493906
6. Namwat, W., et al. 2002. J. Bacteriol. 184: 4811-4818. PMID: 12169606

Physical State :
Solid
Derived From :
Streptomyces sp.
Solubility :
Soluble in ethanol, methanol, DMSO, DMF, and water (limited).
Storage :
Store at -20° C
Melting Point :
240-242° C
Boiling Point :
~1182.9° C at 760 mmHg (Predicted)
Density :
~1.4 g/cm3 (Predicted)
Refractive Index :
n20D 1.65 (Predicted)
pK Values :
pKa: 3.52 (Predicted), pKb: 5.11 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
PubChem CID :
Merck Index :
14: 10004
EC Number :
245-462-6
SMILES :
CC[[email protected]@H]1C(=O)N2CCC[[email protected]]2C(=O)N([[email protected]](C(=O)N3CCC(=O)C[[email protected]]3C(=O)N[[email protected]](C(=O)O[[email protected]@H]([[email protected]@H](C(=O)N1)NC(=O)C4=C(C=CC=N4)O)C)C5=CC=CC=C5)CC6=CC=CC=C6)C

Download SDS (MSDS)

Certificate of Analysis

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Rated 5 out of 5 by from Qiu Qiu, Y. et al. (PubMed 22934408) used a liquid chromatography-tandem mass spectrometry method to determine Virginiamycin S1 and M1 residues in livestock and poultry products. -SCBT Publication Review
Date published: 2015-05-28
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