Molecular structure of Vatalanib Dihydrochloride, CAS Number: 212141-51-0
Vatalanib Dihydrochloride (CAS 212141-51-0)
Alternate Names:
N-(4-Chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine dihydrochloride
Application:
Vatalanib Dihydrochloride is a potent inhibitor of EGFR- and RET-dependent tumor cell proliferation and survival
CAS Number:
212141-51-0
Purity:
≥96%
Molecular Weight:
419.73
Molecular Formula:
C20H15ClN4•2HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
Vandetanib inhibits VEGFR-dependent tumor angiogenesis and EGFR- and RET-dependent tumor cell proliferation and survival. Vandetanib is the active ingredient in the drug sold under the trade name Zactima® and is approved for treatment of patients with follicular, medullary, anaplastic, and locally advanced and metastatic papillary thyroid cancer.
Vatalanib Dihydrochloride (CAS 212141-51-0) References
- Vandetanib (ZD6474): an orally available receptor tyrosine kinase inhibitor that selectively targets pathways critical for tumor growth and angiogenesis. | Herbst, RS., et al. 2007. Expert Opin Investig Drugs. 16: 239-49. PMID: 17243944
Inhibitor of:
c-Kit, EGFR, Flk-1, PDGFR-beta, and Ret.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Vatalanib Dihydrochloride, 5 mg | sc-202379 | 5 mg | $125.00 | |||
Vatalanib Dihydrochloride, 25 mg | sc-202379A | 25 mg | $374.00 |