Valproic Acid Antibody (802): sc-58067

Valproic Acid Antibody (802) is a mouse monoclonal IgG1 antibody that detects Valproic Acid in non-species reactive samples through enzyme-linked immunosorbent assay (ELISA). Valproic Acid is a crucial fatty acid primarily recognized for its role as an anticonvulsant and mood-stabilizing agent, particularly in the treatment of epilepsy and bipolar disorder, while also being utilized for migraine headaches and schizophrenia. Valproic Acid′s function is significant as Valproic Acid negatively impacts the inhibitory neurotransmission mediated by the neurotransmitter gamma-Aminobutyric acid (GABA), which is essential for maintaining the balance of excitation and inhibition in the central nervous system. Additionally, Valproic Acid acts as an inhibitor of histone deacetylase 1 (HDAC1), linking Valproic Acid to neuroprotective strategies in HIV therapy. By increasing GABA levels in the brain or modifying the characteristics of voltage-dependent sodium channels, Valproic Acid plays a vital role in neuroprotection and mood stabilization. With a molecular weight of 144.211 g/mol and a half-life of 9-16 hours, Valproic Acid is primarily metabolized in the liver to its glucuronide conjugate, making Valproic Acid an important therapeutic agent with potential side effects such as dyspepsia and weight gain. Anti-Valproic Acid antibody (802) is an invaluable tool for researchers studying the multifaceted roles of Valproic Acid in various neurological conditions.