Molecular structure of (+)-U-50488 hydrochloride, CAS Number: 67198-17-8
(+)-U-50488 hydrochloride (CAS 67198-17-8)
Alternate Names:
trans-(+)-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)-cyclohexyl]benzeneacetamide hydrochloride
Application:
(+)-U-50488 hydrochloride is an enantiomer of (±)-U-50488
CAS Number:
67198-17-8
Purity:
≥98%
Molecular Weight:
405.79
Molecular Formula:
C19H26Cl2N2O•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Available in US only.
Available in US only.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
(+)-U-50488 hydrochloride is a less active enantiomer of (±)-U-50488. This compound is an agonist of the KOR (κ-opioid rececptor).
(+)-U-50488 hydrochloride (CAS 67198-17-8) References
- Activation of peripheral ATP-sensitive K+ channels mediates the antinociceptive effect of Crotalus durissus terrificus snake venom. | Picolo, G., et al. 2003. Eur J Pharmacol. 469: 57-64. PMID: 12782185
- Isopathic versus enantiomeric inhibition of U-50488 HCl toxicity--experimental studies. | Kuzeff, RM., et al. 2009. Homeopathy. 98: 83-7. PMID: 19358960
- Pharmacological activities of optically pure enantiomers of the kappa opioid agonist, U50,488, and its cis diastereomer: evidence for three kappa receptor subtypes. | Rothman, RB., et al. 1989. Eur J Pharmacol. 167: 345-53. PMID: 2553442
Activator of:
KOR.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(+)-U-50488 hydrochloride, 10 mg | sc-203712 | 10 mg | $155.00 | |||
| US: Only available in the US | ||||||
(+)-U-50488 hydrochloride, 50 mg | sc-203712A | 50 mg | $645.00 | |||
| US: Only available in the US | ||||||