Molecular structure of U-44069, CAS Number: 56985-32-1
U-44069 (CAS 56985-32-1)
Application:
U-44069 is a prostaglandin endoperoxide receptor agonist/antagonist
CAS Number:
56985-32-1
Molecular Weight:
350.5
Molecular Formula:
C21H34O4
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
U-44069 is a prostaglandin endoperoxide receptor agonist. U-44069 is an activator of TXA2R. U-44069 is a stable analog of the endoperoxide PGH2.
U-44069 (CAS 56985-32-1) References
- Identification of CYP4F8 in human seminal vesicles as a prominent 19-hydroxylase of prostaglandin endoperoxides. | Bylund, J., et al. 2000. J Biol Chem. 275: 21844-9. PMID: 10791960
- Contractile properties of lymphatics from the human lower leg. | Sjöberg, T. and Steen, S. 1991. Lymphology. 24: 16-21. PMID: 1646914
- Pre- and postjunctional effects of some prostanoids in human isolated vas deferens. | Holmquist, F., et al. 1991. Am J Physiol. 260: R792-7. PMID: 1707245
- Thromboxane A2-mimetics are potent microvascular permeability factors in the conjunctiva. | Woodward, DF., et al. 1990. J Pharmacol Exp Ther. 255: 23-7. PMID: 2213558
- The pharmacology of L-670,596, a potent and selective thromboxane/prostaglandin endoperoxide receptor antagonist. | Ford-Hutchinson, AW., et al. 1989. Can J Physiol Pharmacol. 67: 989-93. PMID: 2598135
- Differential regulation of the cyclooxygenase pathway in starch elicited rat peritoneal macrophages by prostaglandin E2, U-44069, a stable endoperoxide analogue and dibutyryl-cyclic AMP. | Elliott, GR., et al. 1985. Eur J Pharmacol. 114: 71-4. PMID: 2995076
- Low concentrations of the stable prostaglandin endoperoxide U44069 stimulate shape change in quin2-loaded platelets without a measurable increase in [Ca2+]i. | Simpson, AW., et al. 1986. FEBS Lett. 201: 301-5. PMID: 3086128
- Contractile effects of TxA2 and endoperoxide analogues on cultured rat glomerular mesangial cells. | Mené, P. and Dunn, MJ. 1986. Am J Physiol. 251: F1029-35. PMID: 3538903
- Reversal of renal and smooth muscle actions of the thromboxane mimetic U-44069 by diltiazem. | Loutzenhiser, R., et al. 1986. Am J Physiol. 250: F619-26. PMID: 3963201
- Thromboxane-induced phosphatidate formation in human platelets. Relationship to receptor occupancy and to changes in cytosolic free calcium. | Pollock, WK., et al. 1984. Biochem J. 219: 833-42. PMID: 6234886
- Quantitative pharmacologic responses of normal and atherosclerotic isolated human epicardial coronary arteries. | Ginsburg, R., et al. 1984. Circulation. 69: 430-40. PMID: 6690108
- Mechanism of activation of isolated rabbit aorta by PGH2 analogue U-44069. | Loutzenhiser, R. and van Breemen, C. 1981. Am J Physiol. 241: C243-9. PMID: 6795928
Activator of:
TXA2R.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
U-44069, 1 mg | sc-202848 | 1 mg | $151.00 | |||
U-44069, 5 mg | sc-202848A | 5 mg | $667.00 |