Date published: 2026-5-18

1-800-457-3801

SCBT Portrait Logo
Seach Input

Tris(2-ethylhexyl) phosphate (CAS 78-42-2)

0.0(0)
Write a reviewAsk a question

See product citations (9)

Alternate Names:
′Trioctyl′ phosphate
CAS Number:
78-42-2
Purity:
≥98%
Molecular Weight:
434.63
Molecular Formula:
C24H51O4P
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

Tris(2-ethylhexyl) phosphate, known as TEHP, is a versatile colorless liquid with a faint, recognizable scent. As a member of the phosphate family, which encompasses phosphorus and oxygen-containing compounds, Tris(2-ethylhexyl) phosphate excels as an efficient flame retardant widely utilized in industries such as automotive and electronics. The flame retardant properties of Tris(2-ethylhexyl) phosphate stem from its ability to create a protective layer around treated materials. Upon reaction with the material, Tris(2-ethylhexyl) phosphate generates a char layer that hinders further combustion. Acting as a surfactant, Tris(2-ethylhexyl) phosphate reduces the surface tension of liquids, enabling their dispersion into smaller particles. Lastly, Tris(2-ethylhexyl) phosphate functions as a plasticizer, decreasing material viscosity and augmenting flexibility.


Tris(2-ethylhexyl) phosphate (CAS 78-42-2) References

  1. NTP Toxicology and Carcinogenesis Studies of Tris(2-ethylhexyl)phosphate (CAS No. 78-42-2) In F344/N Rats and B6C3F1 Mice (Gavage Studies).  |  ,. 1984. Natl Toxicol Program Tech Rep Ser. 274: 1-178. PMID: 12748680
  2. Organophosphate flame retardants and plasticizers in indoor air.  |  Hartmann, PC., et al. 2004. Chemosphere. 57: 781-7. PMID: 15488569
  3. Tris(2-ethylhexyl)phosphate as an extractant for trivalent gallium, indium and thallium.  |  Nambiar, DC., et al. 1994. Talanta. 41: 1951-5. PMID: 18966155
  4. Separation of scandium(III) and yttrium(III) by tris(2-ethylhexyl)phosphate (TEHP).  |  Chhatre, MH. and Shinde, VM. 1998. Talanta. 47: 413-9. PMID: 18967342
  5. [ORGANOPHOSPHORUS FLAME RETARDANTS - TOXICITY AND INFLUENCE ON HUMAN HEALTH].  |  Bruchajzer, E., et al. 2015. Med Pr. 66: 235-64. PMID: 26294315
  6. Legacy and emerging organophosphοrus flame retardants in car dust from Greece: Implications for human exposure.  |  Christia, C., et al. 2018. Chemosphere. 196: 231-239. PMID: 29304461
  7. Solvent-stir bar microextraction system using pure tris-(2-ethylhexyl) phosphate as supported liquid membrane: A new and efficient design for the extraction of malondialdehyde from biological fluids.  |  Fashi, A., et al. 2018. Talanta. 182: 299-305. PMID: 29501156
  8. Comparison of tris(2-ethylhexyl) phosphate and di(2-ethylhexyl) phosphoric acid toxicities in a rat 28-day oral exposure study.  |  Pelletier, G., et al. 2020. J Appl Toxicol. 40: 600-618. PMID: 31884710
  9. Tissue-specific bioaccumulation, metabolism and excretion of tris (2-ethylhexyl) phosphate (TEHP) in rare minnow (Gobiocyprisrarus).  |  Hou, R., et al. 2020. Environ Pollut. 261: 114245. PMID: 32220757
  10. Inhibitory effects of organophosphate esters on carboxylesterase activity of rat liver microsomes.  |  Tsugoshi, Y., et al. 2020. Chem Biol Interact. 327: 109148. PMID: 32511959
  11. Discovery of contaminants with antagonistic activity against retinoic acid receptor in house dust.  |  Jia, Y., et al. 2022. J Hazard Mater. 426: 127847. PMID: 34836686
  12. Cyto-Genotoxic and Transcriptomic Alterations in Human Liver Cells by Tris (2-Ethylhexyl) Phosphate (TEHP): A Putative Hepatocarcinogen.  |  Saquib, Q., et al. 2022. Int J Mol Sci. 23: PMID: 35409358
  13. Mechanisms of flame retardant tris (2-ethylhexyl) phosphate biodegradation via novel bacterial strain Ochrobactrum tritici WX3-8.  |  He, J., et al. 2022. Chemosphere. 311: 137071. PMID: 36328323
  14. Insights into the geographical distribution, bioaccumulation characteristics, and ecological risks of organophosphate esters.  |  Yan, Z., et al. 2023. J Hazard Mater. 445: 130517. PMID: 36463749
  15. Comparative chronic toxicities and carcinogenic potentials of 2-ethylhexyl-containing compounds in rats and mice.  |  Kluwe, WM., et al. 1985. Carcinogenesis. 6: 1577-83. PMID: 4053278

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Tris(2-ethylhexyl) phosphate, 25 ml

sc-251393
25 ml
$32.00