Molecular structure of Trehalose dihydrate, cell culture, CAS Number: 6138-23-4
Trehalose dihydrate, cell culture (CAS 6138-23-4)
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Alternate Names:
α,α-Trehalose; D-(+)-Trehalose dihydrate
Application:
Trehalose dihydrate, cell culture is an osmolyte, chemical chaperone, and inducer of autophagy
CAS Number:
6138-23-4
Purity:
≥99%
Molecular Weight:
378.33
Molecular Formula:
C12H22O11•2H2O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Trehalose dihydrate, cell culture is an osmolyte, a chemical chaperone and inducer of autophagy, that has been reported to protect cells against numerous environmental stresses. This compound contains many properties that allow it to stabilize partially unfolded protein molecules and inhibit protein aggregation. These properties include a low chemical reactivity, high glass transition temperature, existence of numerous polymorphs, nonreducing nature, and high affinity for water molecules. Additionally, Trehalose has been noted to bind to expanded polyglutamines and stabilize partially unfolded polyglutamine-containing proteins.
Trehalose dihydrate, cell culture (CAS 6138-23-4) References
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- An impediment to random walk: trehalose microenvironment drives preferential endocytic uptake of plasmonic nanoparticles. | Siddhanta, S., et al. 2016. Chem Sci. 7: 3730-3736. PMID: 30155017
- Trehalose as glucose surrogate in proliferation and cellular mobility of adult neural progenitor cells derived from mouse hippocampus. | Bertl, A., et al. 2019. J Neural Transm (Vienna). 126: 1485-1491. PMID: 31468180
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- Freeze-dried cationic calcium phosphate nanorods as versatile carriers of nucleic acids (DNA, siRNA) | Jan Klesing, Svitlana Chernousova and Matthias Epple *. 23rd July 2011. J. Mater. Chem.,. 2012, 22,: 199-204.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Trehalose dihydrate, cell culture, 10 g | sc-394303 | 10 g | $76.00 | |||
Trehalose dihydrate, cell culture, 25 g | sc-394303A | 25 g | $135.00 | |||
Trehalose dihydrate, cell culture, 100 g | sc-394303B | 100 g | $355.00 |