Thiochrome (CAS 92-35-3)
QUICK LINKS
Thiochrome is a chemical compound primarily recognized for its utility in biochemical research, particularly in studies involving thiamine, also known as vitamin B1. Due to its fluorescent properties, thiochrome is utilized as a sensitive probe for the detection and quantification of thiamine in various biological samples, facilitating research into the vitamin′s role in cellular metabolism. In enzymology, thiochrome serves as a tool to investigate the activity of thiamine diphosphate-dependent enzymes, which are for the catalysis of key metabolic reactions. Additionally, researchers use thiochrome to study the transport and uptake mechanisms of thiamine in living organisms, which is essential for understanding the nutritional and metabolic implications of this vitamin. In analytical chemistry, thiochrome is employed in the development of assays based on high-performance liquid chromatography (HPLC) and fluorescence detection, aiding in the advancement of sensitive analytical techniques.
Thiochrome (CAS 92-35-3) References
- Determination of thiamine by high-performance liquid chromatography. | Lynch, PL. and Young, IS. 2000. J Chromatogr A. 881: 267-84. PMID: 10905711
- THIAMINE: A NOVEL CONVERSION FROM THIOCHROME. | RINSINGER, GE. and PARKER, PN. 1963. Science. 141: 1280-1. PMID: 14059782
- Silver-induced enhancement of thiochrome-based peroxide measurements. | Li, J., et al. 2003. Anal Chem. 75: 6753-8. PMID: 14640758
- Thiochrome enhances acetylcholine affinity at muscarinic M4 receptors: receptor subtype selectivity via cooperativity rather than affinity. | Lazareno, S., et al. 2004. Mol Pharmacol. 65: 257-66. PMID: 14722259
- [Thiochrome inhibition of alcohol dehydrogenase]. | Petrov, SA. 1992. Ukr Biokhim Zh (1978). 64: 91-4. PMID: 1488820
- Thiamine and vasculopathies. | Stepuro, II. 2005. Prostaglandins Leukot Essent Fatty Acids. 72: 115-27. PMID: 15626594
- Flow injection fluorimetric determination of thiamine and copper based on the formation of thiochrome. | Perez-Ruiz, T., et al. 1992. Talanta. 39: 907-11. PMID: 18965470
- Administration of Thiamine and Thiochrome Enhanced Reproduction of Chlorella, Drosophila melanogaster, and Danio. | Petrov, SA., et al. 2016. J Nutr Sci Vitaminol (Tokyo). 62: 6-11. PMID: 27117845
- Photolysis of thiochrome in aqueous solution: A kinetic study. | Anwar, Z., et al. 2020. J Photochem Photobiol B. 203: 111766. PMID: 31927488
- How is vitamin B1 oxidized to thiochrome? Elementary processes revealed by a DFT study. | Yamabe, S., et al. 2021. Org Biomol Chem. 19: 4529-4536. PMID: 33929469
- Fluorometry detection for trypsin via inner filter effect between cytochrome C and in-situ formed fluorescent thiochrome. | Yao, Z., et al. 2021. Talanta. 234: 122614. PMID: 34364423
- A smartphone-based ratiometric fluoroprobe based on blue-red dual-emission signals of thiochrome and copper nanoclusters for sensitive assay of metam-sodium in cucumbers. | Chen, K., et al. 2023. Talanta. 261: 124673. PMID: 37207510
- Determination of urinary thiamin by the thiochrome method. | Dong, MH., et al. 1981. Clin Biochem. 14: 16-8. PMID: 6453672
- A reliable semiautomated method for the determination of total thiamine in whole blood by the thiochrome method with high-performance liquid chromatography. | Schrijver, J., et al. 1982. Ann Clin Biochem. 19: 52-6. PMID: 7065633
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Thiochrome, 100 mg | sc-255658 | 100 mg | $154.00 |