Molecular structure of Thiethylperazine dimalate, CAS Number: 52239-63-1
Thiethylperazine dimalate (CAS 52239-63-1)
Alternate Names:
Hydroxybutanedioic Acid compd. with 2-(Ethylthio)-10-[3-(4-methyl-1-piperazinyl)propyl]-10H-phenothiazine (2:1); 2-(Ethylthio)-10-[3-(4-methyl-1-piperazinyl)propyl]-10H-Phenothiazine Hydroxybutanedioate (1:2); Norzine
Application:
Thiethylperazine dimalate is a potent Enterococcus faecalis inhibitor and antibacterial agent
CAS Number:
52239-63-1
Molecular Weight:
667.80
Molecular Formula:
C22H29N3S2•2C4H6O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Thiethylperazine malate (TPM) is a utilized organic compound in scientific research. Derived from ethylperazine, which belongs to the phenothiazine family, Thiethylperazine malate interacts with specific receptor sites within the central nervous system. These receptor sites encompass serotonin, dopamine, and norepinephrine receptors, among others. By binding to these receptors, Thiethylperazine malate enhances their activity, ultimately resulting in cellular activity modifications.
Thiethylperazine dimalate (CAS 52239-63-1) References
- THE EFFECTS OF THIETHYLPERAZINE DIMALEATE (TORECAN) ON NAUSEA AND VOMITING. | TAMBOLINE, BL., et al. 1965. Can Med Assoc J. 92: 422-3. PMID: 14261157
- A drug-repositioning screen for primary pancreatic ductal adenocarcinoma cells identifies 6-thioguanine as an effective therapeutic agent for TPMT-low cancer cells. | Kim, I., et al. 2018. Mol Oncol. 12: 1526-1539. PMID: 30055072
- A Systematic Screen Reveals a Diverse Collection of Medications That Induce Antifungal Resistance in Candida Species. | Butts, A., et al. 2019. Antimicrob Agents Chemother. 63: PMID: 30858206
- Identification of Off-Patent Compounds That Present Antifungal Activity Against the Emerging Fungal Pathogen Candida auris. | de Oliveira, HC., et al. 2019. Front Cell Infect Microbiol. 9: 83. PMID: 31001487
- Repurposing Approved Drugs as Inhibitors of Kv7.1 and Nav1.8 to Treat Pitt Hopkins Syndrome. | Ekins, S., et al. 2019. Pharm Res. 36: 137. PMID: 31332533
- Identification of Off-Patent Drugs That Show Synergism with Amphotericin B or That Present Antifungal Action against Cryptococcus neoformans and Candida spp. | Rossi, SA., et al. 2020. Antimicrob Agents Chemother. 64: PMID: 31988099
- Current and promising pharmacotherapeutic options for candidiasis. | Scorzoni, L., et al. 2021. Expert Opin Pharmacother. 22: 867-887. PMID: 33538201
- Promising Drug Candidates and New Strategies for Fighting against the Emerging Superbug Candida auris. | Billamboz, M., et al. 2021. Microorganisms. 9: PMID: 33803604
- Emerging and future strategies in the management of recalcitrant Candida auris. | Bandara, N. and Samaranayake, L. 2022. Med Mycol. 60: PMID: 35142862
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Thiethylperazine dimalate, 100 mg | sc-472953 | 100 mg | $281.00 | |||
Thiethylperazine dimalate, 200 mg | sc-472953A | 200 mg | $447.00 | |||
Thiethylperazine dimalate, 1 g | sc-472953B | 1 g | $1727.00 |