Date published: 2026-5-7

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Thailandolide B (CAS 944726-62-9)

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Application:
Thailandolide B is a stereisomer of chrodrimanin B
CAS Number:
944726-62-9
Molecular Weight:
484.60
Molecular Formula:
C27H32O8
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Thailandolide B is a macrocyclic lactone isolated from Streptomyces species discovered in soil samples. Its structure is characterized by a large cyclic ester (lactone) ring, which forms the basis of its unique chemical and biological properties. As a compound within the realm of natural products chemistry, thailandolide B has sparked interest particularly in the study of molecular interactions and bioactivity mechanisms. In scientific research, thailandolide B has been primarily explored for its ability to modulate biological pathways through specific molecular interactions. One notable aspect of its action is the disruption of cellular processes such as signaling pathways and protein synthesis in microorganisms. This makes thailandolide B a valuable tool for studying the effects of macrocyclic lactones on these fundamental biological processes, offering insights into how such molecules can influence cell behavior through non-traditional pathways. Additionally, thailandolide B is used in studies focusing on the synthesis and modification of macrocyclic compounds. Researchers are interested in how alterations to its lactone ring or other molecular appendages affect its stability, reactivity, and interaction with biological macromolecules. These studies contribute to the broader field of synthetic organic chemistry, where the goal is to manipulate and optimize natural structures for enhanced performance in various applications.


Thailandolide B (CAS 944726-62-9) References

  1. Merodrimanes and other constituents from Talaromyces thailandiasis.  |  Dethoup, T., et al. 2007. J Nat Prod. 70: 1200-2. PMID: 17536857
  2. A new meroterpenoid, chrodrimanin C, from YO-2 of Talaromyces sp.  |  Hayashi, H., et al. 2012. Biosci Biotechnol Biochem. 76: 745-8. PMID: 22484942
  3. New chrodrimanin congeners, chrodrimanins D-H, from YO-2 of Talaromyces sp.  |  Hayashi, H., et al. 2012. Biosci Biotechnol Biochem. 76: 1765-8. PMID: 22972343
  4. Induced production of BE-31405 by co-culturing of Talaromyces siamensis FKA-61 with a variety of fungal strains.  |  Nonaka, K., et al. 2015. J Antibiot (Tokyo). 68: 573-8. PMID: 25805070
  5. Coumarins, dihydroisocoumarins, a dibenzo-α-pyrone, a meroterpenoid, and a merodrimane from Talaromyces amestolkiae.  |  El-Elimat, T., et al. 2021. Tetrahedron Lett. 72: PMID: 34421136
  6. Benzoquinone and furopyridinone derivatives from the marine-derived fungus Talaromyces sp. MCCC 3A01752.  |  Hong, X., et al. 2024. Nat Prod Res. 38: 320-326. PMID: 36093561
  7. Meroterpenoids and Steroids from the Marine-Derived Fungus Trametes sp. ZYX-Z-16.  |  Ren, Z., et al. 2022. Molecules. 27: PMID: 36557915
  8. The Outstanding Chemodiversity of Marine-Derived Talaromyces.  |  Nicoletti, R., et al. 2023. Biomolecules. 13: PMID: 37509057
  9. Two new Talaromyces species from soil in Thailand.  |  Manoch and Leka, et al. 2013. Mycoscience. 54.5: 335-342.
  10. Study on the secondary metabolites from the deep-sea-derived fungus Neoroussoella sp. and their biological activities.  |  Jin-qian and Z. H. O. N. G., et al. 2021. NATURAL PRODUCT RESEARCH AND DEVELOPMENT. 33.7: 1165.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Thailandolide B, 1 mg

sc-396529
1 mg
$146.00